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Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia

The aim of this work was the fortification of milk with a bioavailable complex of iron with ascorbic acid and in vivo evaluation of its effect on the hematological parameters of laboratory rats. To do this, we produced sterilized milk with iron and ascorbic acid supplementations. Fortification of mi...

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Главные авторы: Pavlenko, E. N., Павленко, Е. Н., Pavlenko, A. E., Павленко, А. Э., Tikhonov, E. E., Тихонов, Э. Е.
Формат: Статья
Язык:English
Опубликовано: SPER Publications 2024
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Online-ссылка:https://dspace.ncfu.ru/handle/123456789/29218
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spelling ir-123456789-292182024-11-11T09:42:23Z Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia Pavlenko, E. N. Павленко, Е. Н. Pavlenko, A. E. Павленко, А. Э. Tikhonov, E. E. Тихонов, Э. Е. Biochemical parameters Hematological parameters Fe Fortification Vitamin C The aim of this work was the fortification of milk with a bioavailable complex of iron with ascorbic acid and in vivo evaluation of its effect on the hematological parameters of laboratory rats. To do this, we produced sterilized milk with iron and ascorbic acid supplementations. Fortification of milk increased the iron content to 1.0 mg/100 mL and ascorbic acid to 3.0 mg/100 mL, which meets the requirements for iron and ascorbic acid levels in children’s nutrition. An in vivo experiment was performed on 42 male rats of the Wistar line with an initial body weight of 120–240 g. As a result of the study, it was found that administration of milk fortified with iron and ascorbic acid to rats with severe anemia against the background of an iron-deficient diet at a dose of 1.7 mL per 100 g of body weight for 20 days helps to prevent the development of the condition of IDA in animals. The results of the study show the great prospects of using milk fortified with iron and ascorbic acid for the prevention of iron deficiency anemia. 2024-11-11T09:41:27Z 2024-11-11T09:41:27Z 2024 Статья Verevkina M., Gasparian I., Ermakov M., Kozlikin A., Pavlenko E., Pavlenko A., Tikhonov E., Matyukhin A. Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia // Journal of Advanced Pharmacy Education and Research. - 2024. - 14 (1). - pp. 77 - 83. - DOI: 10.51847/INNLMYKXN5 https://dspace.ncfu.ru/handle/123456789/29218 en Journal of Advanced Pharmacy Education and Research application/pdf SPER Publications
institution СКФУ
collection Репозиторий
language English
topic Biochemical parameters
Hematological parameters
Fe
Fortification
Vitamin C
spellingShingle Biochemical parameters
Hematological parameters
Fe
Fortification
Vitamin C
Pavlenko, E. N.
Павленко, Е. Н.
Pavlenko, A. E.
Павленко, А. Э.
Tikhonov, E. E.
Тихонов, Э. Е.
Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia
description The aim of this work was the fortification of milk with a bioavailable complex of iron with ascorbic acid and in vivo evaluation of its effect on the hematological parameters of laboratory rats. To do this, we produced sterilized milk with iron and ascorbic acid supplementations. Fortification of milk increased the iron content to 1.0 mg/100 mL and ascorbic acid to 3.0 mg/100 mL, which meets the requirements for iron and ascorbic acid levels in children’s nutrition. An in vivo experiment was performed on 42 male rats of the Wistar line with an initial body weight of 120–240 g. As a result of the study, it was found that administration of milk fortified with iron and ascorbic acid to rats with severe anemia against the background of an iron-deficient diet at a dose of 1.7 mL per 100 g of body weight for 20 days helps to prevent the development of the condition of IDA in animals. The results of the study show the great prospects of using milk fortified with iron and ascorbic acid for the prevention of iron deficiency anemia.
format Статья
author Pavlenko, E. N.
Павленко, Е. Н.
Pavlenko, A. E.
Павленко, А. Э.
Tikhonov, E. E.
Тихонов, Э. Е.
author_facet Pavlenko, E. N.
Павленко, Е. Н.
Pavlenko, A. E.
Павленко, А. Э.
Tikhonov, E. E.
Тихонов, Э. Е.
author_sort Pavlenko, E. N.
title Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia
title_short Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia
title_full Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia
title_fullStr Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia
title_full_unstemmed Milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia
title_sort milk fortification with a complex of iron with ascorbic acid for control of iron deficiency anemia
publisher SPER Publications
publishDate 2024
url https://dspace.ncfu.ru/handle/123456789/29218
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