Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry

Detergents and disinfectants for dairy industry must meet a variety of characteristics, including low toxicity, high antibacterial activity, and excellent rinsing of pollutants from working surfaces. This work presents an innovative detergent-disinfectant agent based on whey mineralizate and silver...

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Главные авторы:	Blinov, A. V., Блинов, А. В., Blinova, A. A., Блинова, А. А., Nagdalian, A. A., Нагдалян, А. А., Gvozdenko, A. A., Гвозденко, А. А., Golik, A. B., Голик, А. Б., Rekhman, Z. A., Рехман, З. А., Filippov, D. D., Филиппов, Д. Д.
Формат:	Статья
Язык:	English
Опубликовано:	Nature Research 2024
Темы:	Cleaner production Mineralization Colloidal silver Milk Toxicity Whey
Online-ссылка:	https://dspace.ncfu.ru/handle/123456789/29228
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spelling	ir-123456789-292282024-11-12T11:46:58Z Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry Blinov, A. V. Блинов, А. В. Blinova, A. A. Блинова, А. А. Nagdalian, A. A. Нагдалян, А. А. Gvozdenko, A. A. Гвозденко, А. А. Golik, A. B. Голик, А. Б. Rekhman, Z. A. Рехман, З. А. Filippov, D. D. Филиппов, Д. Д. Cleaner production Mineralization Colloidal silver Milk Toxicity Whey Detergents and disinfectants for dairy industry must meet a variety of characteristics, including low toxicity, high antibacterial activity, and excellent rinsing of pollutants from working surfaces. This work presents an innovative detergent-disinfectant agent based on whey mineralizate and silver nanoparticles (Ag NPs), which allows reducing production costs and ensuring high cleanliness of treated surfaces compared to analogues. For this purpose, a method for obtaining sols of Ag NPs stabilized with didecyldimethylammonium bromide (Ag NPs-DDAB) was developed and optimized using neural network algorithms. Characterization of Ag NPs-DDAB showed particles with a radius of 4.5 nm and 20 nm, stable in the pH range from 2 to 11. An acute toxicity study of Ag NPs in mice showed LD50 = 4230 μg/kg. Based on the degree of accumulation and inhalation toxicity, Ag NPs-DDAB are classified as low-hazard chemicals. The developed detergent-disinfectant had a washability of about 90%, high antimicrobial activity (0.005 mg/mL) against Penicillium roqueforti and a sanitary and hygienic effect on coliforms, general contamination and pathogenic microorganisms, a low-corrosive effect and low toxicity (315 mg/mL) to Danio rerio. It was concluded that the use of detergent-disinfectant agent will completely eliminate the consumption of water for the equipment cleaning process and can be used to clean an electrodialysis unit’s circuits, enabling the utilization of secondary waste from membrane milk processing and promoting resource efficiency and cleaner production in the dairy industry. 2024-11-12T11:45:13Z 2024-11-12T11:45:13Z 2024 Статья Blinov A., Blinova A., Nagdalian A., Siddiqui S.A., Gvozdenko A., Golik A., Rekhman Z., Filippov D., Shariati M.A., AL-Farga A., Al-maaqar S.M. Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry // Scientific Reports. - 2024. - 14 (1). - art. no. 23943. - DOI: 10.1038/s41598-024-71542-9 https://dspace.ncfu.ru/handle/123456789/29228 en Scientific Reports application/pdf application/pdf Nature Research
institution	СКФУ
collection	Репозиторий
language	English
topic	Cleaner production Mineralization Colloidal silver Milk Toxicity Whey
spellingShingle	Cleaner production Mineralization Colloidal silver Milk Toxicity Whey Blinov, A. V. Блинов, А. В. Blinova, A. A. Блинова, А. А. Nagdalian, A. A. Нагдалян, А. А. Gvozdenko, A. A. Гвозденко, А. А. Golik, A. B. Голик, А. Б. Rekhman, Z. A. Рехман, З. А. Filippov, D. D. Филиппов, Д. Д. Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry
description	Detergents and disinfectants for dairy industry must meet a variety of characteristics, including low toxicity, high antibacterial activity, and excellent rinsing of pollutants from working surfaces. This work presents an innovative detergent-disinfectant agent based on whey mineralizate and silver nanoparticles (Ag NPs), which allows reducing production costs and ensuring high cleanliness of treated surfaces compared to analogues. For this purpose, a method for obtaining sols of Ag NPs stabilized with didecyldimethylammonium bromide (Ag NPs-DDAB) was developed and optimized using neural network algorithms. Characterization of Ag NPs-DDAB showed particles with a radius of 4.5 nm and 20 nm, stable in the pH range from 2 to 11. An acute toxicity study of Ag NPs in mice showed LD50 = 4230 μg/kg. Based on the degree of accumulation and inhalation toxicity, Ag NPs-DDAB are classified as low-hazard chemicals. The developed detergent-disinfectant had a washability of about 90%, high antimicrobial activity (0.005 mg/mL) against Penicillium roqueforti and a sanitary and hygienic effect on coliforms, general contamination and pathogenic microorganisms, a low-corrosive effect and low toxicity (315 mg/mL) to Danio rerio. It was concluded that the use of detergent-disinfectant agent will completely eliminate the consumption of water for the equipment cleaning process and can be used to clean an electrodialysis unit’s circuits, enabling the utilization of secondary waste from membrane milk processing and promoting resource efficiency and cleaner production in the dairy industry.
format	Статья
author	Blinov, A. V. Блинов, А. В. Blinova, A. A. Блинова, А. А. Nagdalian, A. A. Нагдалян, А. А. Gvozdenko, A. A. Гвозденко, А. А. Golik, A. B. Голик, А. Б. Rekhman, Z. A. Рехман, З. А. Filippov, D. D. Филиппов, Д. Д.
author_facet	Blinov, A. V. Блинов, А. В. Blinova, A. A. Блинова, А. А. Nagdalian, A. A. Нагдалян, А. А. Gvozdenko, A. A. Гвозденко, А. А. Golik, A. B. Голик, А. Б. Rekhman, Z. A. Рехман, З. А. Filippov, D. D. Филиппов, Д. Д.
author_sort	Blinov, A. V.
title	Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry
title_short	Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry
title_full	Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry
title_fullStr	Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry
title_full_unstemmed	Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry
title_sort	sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry
publisher	Nature Research
publishDate	2024
url	https://dspace.ncfu.ru/handle/123456789/29228
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Sustainable detergent-disinfectant agent based on whey mineralizate and silver nanoparticles for cleaner production in dairy industry

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