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6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties

6-Bromo- and 6,7-dibromo-1,3-dimethyl-1H-perimidin-2(3H)-ones were arylated with arylboronic acids under Suzuki–Miyaura reaction conditions to afford 6-aryl-, 6-bromo-7-aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones. A comparison of the X-ray structural parameters of peri-diaryl derivativ...

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Autors principals: Demidov, O. P., Демидов, О. П.
Format: Статья
Idioma:English
Publicat: Royal Society of Chemistry 2025
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Accés en línia:https://dspace.ncfu.ru/handle/123456789/29599
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spelling ir-123456789-295992025-02-03T13:52:31Z 6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties Demidov, O. P. Демидов, О. П. Alkylation Crystals structures Isomerization Isomers Naphthalene Synthesis (chemical) Arylboronic acids Conformational stabilities; H NMR spectroscopy Property Proton sponge Reaction conditions Structural parameter Suzuki-Miyaura reaction Nuclear magnetic resonance spectroscopy 6-Bromo- and 6,7-dibromo-1,3-dimethyl-1H-perimidin-2(3H)-ones were arylated with arylboronic acids under Suzuki–Miyaura reaction conditions to afford 6-aryl-, 6-bromo-7-aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones. A comparison of the X-ray structural parameters of peri-diaryl derivatives of 1,3-dimethyl-1H-perimidin-2(3H)-one, naphthalene and 1,8-bis(dimethylamino)naphthalene (proton sponge) was performed. Based on the data of dynamic 1H NMR spectroscopy and quantum-chemical calculations, barriers to syn/anti-isomerization of 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones were estimated. The optical properties of 6-aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones as structural analogs of fluorophoric 6-aryl- and 6,7-diaryl-1,8-naphthalimides were studied. 2025-02-03T13:51:07Z 2025-02-03T13:51:07Z 2024 Статья Dyatlov, A.L., Filatova, E.A., Pozharskii, A.F., Marchenko, S.S., Demidov, O.P., Chernyshev, A.V., Metelitsa, A.V., Brig, S.S., Medvedev, M.G., Bekmansurov, D.R., Morozov, P.G., Gulevskaya, A.V. 6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties // Organic and Biomolecular Chemistry. - 2024. - 23 (4). - pp. 948-959. - DOI: 10.1039/d4ob01680g https://dspace.ncfu.ru/handle/123456789/29599 en Organic and Biomolecular Chemistry application/pdf application/pdf Royal Society of Chemistry
institution СКФУ
collection Репозиторий
language English
topic Alkylation
Crystals structures
Isomerization
Isomers
Naphthalene
Synthesis (chemical)
Arylboronic acids
Conformational stabilities;
H NMR spectroscopy
Property
Proton sponge
Reaction conditions
Structural parameter
Suzuki-Miyaura reaction
Nuclear magnetic resonance spectroscopy
spellingShingle Alkylation
Crystals structures
Isomerization
Isomers
Naphthalene
Synthesis (chemical)
Arylboronic acids
Conformational stabilities;
H NMR spectroscopy
Property
Proton sponge
Reaction conditions
Structural parameter
Suzuki-Miyaura reaction
Nuclear magnetic resonance spectroscopy
Demidov, O. P.
Демидов, О. П.
6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties
description 6-Bromo- and 6,7-dibromo-1,3-dimethyl-1H-perimidin-2(3H)-ones were arylated with arylboronic acids under Suzuki–Miyaura reaction conditions to afford 6-aryl-, 6-bromo-7-aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones. A comparison of the X-ray structural parameters of peri-diaryl derivatives of 1,3-dimethyl-1H-perimidin-2(3H)-one, naphthalene and 1,8-bis(dimethylamino)naphthalene (proton sponge) was performed. Based on the data of dynamic 1H NMR spectroscopy and quantum-chemical calculations, barriers to syn/anti-isomerization of 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones were estimated. The optical properties of 6-aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones as structural analogs of fluorophoric 6-aryl- and 6,7-diaryl-1,8-naphthalimides were studied.
format Статья
author Demidov, O. P.
Демидов, О. П.
author_facet Demidov, O. P.
Демидов, О. П.
author_sort Demidov, O. P.
title 6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties
title_short 6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties
title_full 6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties
title_fullStr 6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties
title_full_unstemmed 6-Aryl- and 6,7-diaryl-1,3-dimethyl-1H-perimidin-2(3H)-ones: synthesis, conformational stability, crystal structure and optical properties
title_sort 6-aryl- and 6,7-diaryl-1,3-dimethyl-1h-perimidin-2(3h)-ones: synthesis, conformational stability, crystal structure and optical properties
publisher Royal Society of Chemistry
publishDate 2025
url https://dspace.ncfu.ru/handle/123456789/29599
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AT demidovop 6aryland67diaryl13dimethyl1hperimidin23honessynthesisconformationalstabilitycrystalstructureandopticalproperties
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