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Synthesis of 2,2-Dimethyl-2,3-dihydropyrido[3′,2′:4,5]-thieno[3,2-d]pyrimidin-4(1H)-ones by Reaction of 3-Aminothieno[2,3-b]pyridine-2-carboxamides with Acetone

The reaction of 3-aminothieno[2,3-b]pyridin-2-carboxamides with acetone in the presence of catalytic amounts of TsOH under reflux afforded a series of new 2,2-dimethyl-2,3-dihydropyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(1H)-ones in 88–95% yields. Possible protein targets for the new compounds were...

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Auteurs principaux: Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Format: Статья
Langue:English
Publié: Pleiades Publishing 2025
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Accès en ligne:https://dspace.ncfu.ru/handle/123456789/30521
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