Pseudo Four-Component Cyclocondensation of N-Alkylpiperidin-4-ones, Malononitrile, and Acetone
New 8-amino-10-methyl-3-azaspiro[5.5]undeca-8,10-dien-7,7,9-tricarbonitriles were synthesized in 72 and 67% yields by condensation of N-benzyl- or N-ethyl-4-piperidone with malononitrile and acetone in ethanol in the presence of morpholine. The molecular and crystal structures of 8-amino-3-benzyl-10...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , |
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| التنسيق: | Статья |
| اللغة: | English |
| منشور في: |
Pleiades Publishing
2025
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://dspace.ncfu.ru/handle/123456789/31830 |
| الوسوم: |
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| الملخص: | New 8-amino-10-methyl-3-azaspiro[5.5]undeca-8,10-dien-7,7,9-tricarbonitriles were synthesized in 72 and 67% yields by condensation of N-benzyl- or N-ethyl-4-piperidone with malononitrile and acetone in ethanol in the presence of morpholine. The molecular and crystal structures of 8-amino-3-benzyl-10-methyl-3-azaspiro[5.5]undeca-8,10-dien-7,7,9-tricarbonitrile were studied by single crystal X-ray diffraction analysis. |
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