Electrophilically activated nitroalkanes in reaction with aliphatic diamines en route to imidazolines

Electrophilically activated nitroalkanes in reaction with aliphatic diamines en route to imidazolines

A novel synthetic methodology for the assembly of imidazolines via an unusual reaction between nitroalkanes and aliphatic 1,2-diamines in the presence of phosphorous acid is described. In contrast to the related highly efficient preparation of benzimidazoles from aromatic amines, this process repres...

Полное описание

Сохранить в:

Библиографические подробности
Главные авторы:	Aksenov, A. V., Аксенов, А. В., Aksenov, N. A., Аксенов, Н. А., Arutiunov, N. A., Арутюнов, Н. А., Malyuga, V. V., Малюга, В. В., Ovcharov, S. N., Овчаров, С. Н., Rubin, M. A., Рубин, М. А.
Формат:	Статья
Язык:	English
Опубликовано:	Royal Society of Chemistry 2019
Темы:	Amines Aliphatic diamines Aromatic amines Benzimidazoles En-route Imidazolines Nitroalkanes Phosphorous acid Synthetic methodology Paraffins
Online-ссылка:	https://dspace.ncfu.ru/handle/20.500.12258/10138
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!

Схожие документы

Synthesis of 11H-indolo[3,2-c]quinolines by SnCl4-catalyzed cyclization of indole-3-carbaldehyde oximes
Автор: Aksenov, N. A., и др.
Опубликовано: (2020)

Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene
Автор: Aksenov, N. A., и др.
Опубликовано: (2023)

Mn-mediated sequential three-component domino Knoevenagel/cyclization/Michael addition/oxidative cyclization reaction towards annulated imidazo[1,2-a]pyridines
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)

Dual role of polyphosphoric acid-activated nitroalkanes in oxidative peri -annulations: Efficient synthesis of 1,3,6,8-tetraazapyrenes
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

One-pot synthesis of 4-methyl-2-alkyl quinazoline-N-oxides by cascade acetamidation–acylation of simple electron-rich arenes with primary nitroalkanes
Автор: Grishin, I. Y., и др.
Опубликовано: (2025)

Preparation of stereodefined 2-(3-Oxoindolin-2-yl)-2-arylacetonitriles via one-pot reaction of indoles with nitroalkenes
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)

Benzimidazoles and benzoxazoles via the nucleophilic addition of anilines to nitroalkanes
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

One-pot synthesis of benzoxazoles via the metal-free ortho-C-H functionalization of phenols with nitroalkanes
Автор: Aksenov, N. A., и др.
Опубликовано: (2018)

Michael addition to 3-(2-nitrovinyl)indoles – route toward aliphatic nitro compounds with heterocyclic substituents
Автор: Aksenov, N. A., и др.
Опубликовано: (2019)

Electrophilically activated nitroalkanes in synthesis of 3,4-dihydroquinozalines
Автор: Aksenov, A. V., и др.
Опубликовано: (2021)

A facile approach to the synthesis of 3,4-dihydro-2H-benzo[4,5]imidazo[2,1-b][1,3,4]thiadiazines
Автор: Pobedinskaya, D. Y., и др.
Опубликовано: (2024)

Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity
Автор: Aksenov, N. A., и др.
Опубликовано: (2020)

γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles
Автор: Aksenov, N. A., и др.
Опубликовано: (2024)

Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)

Does electrophilic activation of nitroalkanes in polyphosphoric acid involve formation of nitrile oxides?
Автор: Aksenov, A. V., и др.
Опубликовано: (2021)

Electrophilically activated nitroalkanes in the synthesis of substituted 1,3,4-oxadiazoles from amino acid derivatives
Автор: Aksenov, A. V., и др.
Опубликовано: (2022)

A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines
Автор: Aksenov, A. V., и др.
Опубликовано: (2022)

Electrophilically activated nitroalkanes in double annulation of [1,2,4]triazolo[4,3-a]quinolines and 1,3,4-oxadiazole rings
Автор: Aksenov, A. V., и др.
Опубликовано: (2021)

Preparation of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles via chemoselective сyclocondensation of electrophilically activated nitroalkanes to (thio)semicarbazides or thiohydrazides
Автор: Aksenov, N. A., и др.
Опубликовано: (2020)

Electrophilically activated nitroalkanes in the synthesis of 6,7-dihydro-1H-cyclopenta[g]perimidines
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Synthesis of 3,4-dihydroisoquinolines using nitroalkanes in polyphosphoric acid
Автор: Aksenov, N. A., и др.
Опубликовано: (2019)

Synthesis of New 2,2':6',2''-Terpyridin Series with Directly Linked Benzimidazole Moieties
Автор: Demidov, O. P., и др.
Опубликовано: (2025)

Introduction of tetrazol-1-yl and 5-methyltetrazol-1-yl substituents in the phenyl ring of dibenzo-18-crown-6
Автор: Aksenov, N. A., и др.
Опубликовано: (2018)

Modern trends of organic chemistry in russian universities
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Organic Chemistry in Russian Universities. Achievements of Recent Years
Автор: Aksenov, D. A., и др.
Опубликовано: (2024)

Dibenzoylmethane in the Synthesis of Selenium Di- and Tetrahydropyridine-3-carbonitriles
Автор: Aksenov, N. A., и др.
Опубликовано: (2025)

New photochromic indoline spiropyrans containing cationic substituent in the 2H-chromene moiety
Автор: Aksenov, N. A., и др.
Опубликовано: (2018)

Synthesis of New (2E,4E)-2-Cyano-5-phenylpenta-2,4-dienethioamide Derivatives
Автор: Aksenov, N. A., и др.
Опубликовано: (2025)

On the structure of zinc(II) coordination compounds with l-histidine
Автор: Aksenov, N. A., и др.
Опубликовано: (2020)

Synthesis of (2E,4E)-2-(4-Aryl-1,3-selenazol-2-yl)-5-phenylpenta-2,4-dienenitriles
Автор: Aksenov, N. A., и др.
Опубликовано: (2025)

Structure and properties of europium (III) triaquatriglycinate chloride
Автор: Aksenov, N. A., и др.
Опубликовано: (2020)

Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N
Автор: Aksenov, N. A., и др.
Опубликовано: (2022)

A new series of acetohydroxamates shows in vitro and in vivo anticancer activity against melanoma
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)

The chemistry of heterocycles in the 21st century
Автор: Dotsenko, V. V., и др.
Опубликовано: (2024)

Synthesis of chromenoimidazocarbolines by a reaction of quaternary iminium salts with o-hydroxybenzaldehydes
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Reaction of benzyne with 1,2,3,4-tetrahydroisoquinolines as an access to 1H-3-benzazepines
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Reactions of 3,4-dihydroisoquinolines and dihydrothieno[3,2-c]pyridines with benzyne
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Domino reactions of 1-substituted N-(cyanomethyl)isoquinolinium salts with salicylic aldehydes
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

A facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)