Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis

An expeditious click-click cyclize strategy for the assembly of medium-sized heterocyclic rings is described. The sequence involves the reaction of cycloprop-2-ene carboxylic acids with unsaturated amines to furnish amides, which are further subjected to a Cu-catalyzed directed carbomagnesiation and...

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Egile Nagusiak:	Rubin, M. A., Рубин, М. А.
Formatua:	Статья
Hizkuntza:	English
Argitaratua:	American Chemical Society 2020
Gaiak:	Cycloaddition Reaction Cyclopropenes Vinylcarbene
Sarrera elektronikoa:	https://dspace.ncfu.ru/handle/20.500.12258/12117
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id	ir-20.500.12258-12117
record_format	dspace
spelling	ir-20.500.12258-121172020-07-29T09:32:20Z Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis Rubin, M. A. Рубин, М. А. Cycloaddition Reaction Cyclopropenes Vinylcarbene An expeditious click-click cyclize strategy for the assembly of medium-sized heterocyclic rings is described. The sequence involves the reaction of cycloprop-2-ene carboxylic acids with unsaturated amines to furnish amides, which are further subjected to a Cu-catalyzed directed carbomagnesiation and a ring-closing olefin metathesis reaction. This methodology allows for the efficient preparation of lactams with ring sizes up to 10 2020-06-25T13:11:19Z 2020-06-25T13:11:19Z 2020 Статья Yamanushkin, P., Smith, S.P., Petillo, P.A., Rubin, M. Cyclopropene-Templated Assembly of Medium Cycles via Ru-Catalyzed Ring-Closing Metathesis // Organic Letters. - 2020. - Volume 22. - Issue 9. - Pages 3542-3546 http://hdl.handle.net/20.500.12258/12117 en Organic Letters application/pdf application/pdf American Chemical Society
institution	СКФУ
collection	Репозиторий
language	English
topic	Cycloaddition Reaction Cyclopropenes Vinylcarbene
spellingShingle	Cycloaddition Reaction Cyclopropenes Vinylcarbene Rubin, M. A. Рубин, М. А. Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis
description	An expeditious click-click cyclize strategy for the assembly of medium-sized heterocyclic rings is described. The sequence involves the reaction of cycloprop-2-ene carboxylic acids with unsaturated amines to furnish amides, which are further subjected to a Cu-catalyzed directed carbomagnesiation and a ring-closing olefin metathesis reaction. This methodology allows for the efficient preparation of lactams with ring sizes up to 10
format	Статья
author	Rubin, M. A. Рубин, М. А.
author_facet	Rubin, M. A. Рубин, М. А.
author_sort	Rubin, M. A.
title	Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis
title_short	Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis
title_full	Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis
title_fullStr	Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis
title_full_unstemmed	Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis
title_sort	cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis
publisher	American Chemical Society
publishDate	2020
url	https://dspace.ncfu.ru/handle/20.500.12258/12117
work_keys_str_mv	AT rubinma cyclopropenetemplatedassemblyofmediumcyclesviarucatalyzedringclosingmetathesis AT rubinma cyclopropenetemplatedassemblyofmediumcyclesviarucatalyzedringclosingmetathesis
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Cyclopropene-templated assembly of medium cycles via ru-catalyzed ring-closing metathesis

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