Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity

Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity

We discovered a reaction of nitroalkanes with 2-hydrazinylquinolines, 2-hydrazinylpyridines and bis-2,4-dihydrazinylpyrimidines in polyphosphoric acid (PPA) affording 1,2,4-triazolo[4,3-a]quinolines, 1,2,4-triazolo[4,3-a]pyridines and bis[1,2,4]triazolo[4,3-a:4',3'-c]pyrimidines, respectiv...

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मुख्य लेखकों:	Aksenov, N. A., Аксенов, Н. А., Aksenov, A. V., Аксенов, А. В., Kirilov, N. K., Кирилов, Н. К., Arutiunov, N. A., Арутюнов, Н. А., Aksenov, D. A., Аксенов, Д. А., Rubin, M. A., Рубин, М. А.
स्वरूप:	Статья
भाषा:	English
प्रकाशित:	NLM (Medline) 2020
विषय:	Neuroblastoma Nitroalkanes Synthesis of triazole-fused heterocycles Neuroblastoma therapy
ऑनलाइन पहुंच:	https://dspace.ncfu.ru/handle/20.500.12258/13876
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Reactions of 3,4-dihydroisoquinolines and dihydrothieno[3,2-c]pyridines with benzyne
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