इसे छोड़कर सामग्री पर बढ़ने के लिए
Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters

Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters

Cascade reaction of 2 equiv. of furfural (or equimolar amounts of furfural and aromatic aldehyde) with secondary amines and ethyl cyanoacetate afforded diethyl esters of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids with yields of 37–54%. Antimicrobial activity...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Dotsenko, V. V., Доценко, В. В.
स्वरूप: Статья
भाषा:English
प्रकाशित: Pleiades journals 2020
विषय:
Aza-Piancatelli rearrangement
Bicyclo[3.2.1]octane
Furfural
Nazarov reaction
Stenhouse salts
ऑनलाइन पहुंच:https://dspace.ncfu.ru/handle/20.500.12258/14216
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
id ir-20.500.12258-14216
record_format dspace
spelling ir-20.500.12258-142162020-10-02T12:54:14Z Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters Dotsenko, V. V. Доценко, В. В. Aza-Piancatelli rearrangement Bicyclo[3.2.1]octane Furfural Nazarov reaction Stenhouse salts Cascade reaction of 2 equiv. of furfural (or equimolar amounts of furfural and aromatic aldehyde) with secondary amines and ethyl cyanoacetate afforded diethyl esters of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids with yields of 37–54%. Antimicrobial activity of a number of obtained compounds in vitro was studied, and biological activity in silico was analyzed. The obtained bicyclo[3.2.1]octanes are inactive or exhibit weak fungicidal activity, but exhibit moderate bactericidal effect 2020-09-29T10:07:48Z 2020-09-29T10:07:48Z 2020 Статья Ismiyev, A.I., Shoaib, M., Dotsenko, V.V., Ganbarov, K.G., Israilova, A.A., Magerramov, A.M. Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters // Russian Journal of General Chemistry. - 2020. - Volume 90. - Issue 8. - Pages 1418-1425 http://hdl.handle.net/20.500.12258/14216 en Russian Journal of General Chemistry application/pdf application/pdf Pleiades journals
institution СКФУ
collection Репозиторий
language English
topic Aza-Piancatelli rearrangement
Bicyclo[3.2.1]octane
Furfural
Nazarov reaction
Stenhouse salts
spellingShingle Aza-Piancatelli rearrangement
Bicyclo[3.2.1]octane
Furfural
Nazarov reaction
Stenhouse salts
Dotsenko, V. V.
Доценко, В. В.
Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
description Cascade reaction of 2 equiv. of furfural (or equimolar amounts of furfural and aromatic aldehyde) with secondary amines and ethyl cyanoacetate afforded diethyl esters of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids with yields of 37–54%. Antimicrobial activity of a number of obtained compounds in vitro was studied, and biological activity in silico was analyzed. The obtained bicyclo[3.2.1]octanes are inactive or exhibit weak fungicidal activity, but exhibit moderate bactericidal effect
format Статья
author Dotsenko, V. V.
Доценко, В. В.
author_facet Dotsenko, V. V.
Доценко, В. В.
author_sort Dotsenko, V. V.
title Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
title_short Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
title_full Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
title_fullStr Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
title_full_unstemmed Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
title_sort synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
publisher Pleiades journals
publishDate 2020
url https://dspace.ncfu.ru/handle/20.500.12258/14216
work_keys_str_mv AT dotsenkovv synthesisandbiologicalactivityof8dialkylamino3aryl6oxo24dicyanobicyclo321octane24dicarboxylicacidsdiethylesters
AT docenkovv synthesisandbiologicalactivityof8dialkylamino3aryl6oxo24dicyanobicyclo321octane24dicarboxylicacidsdiethylesters
_version_ 1760601723521466368

समान संसाधन