Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
Cascade reaction of 2 equiv. of furfural (or equimolar amounts of furfural and aromatic aldehyde) with secondary amines and ethyl cyanoacetate afforded diethyl esters of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids with yields of 37–54%. Antimicrobial activity...
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Main Authors: | Dotsenko, V. V., Доценко, В. В. |
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Format: | Статья |
Language: | English |
Published: |
Pleiades journals
2020
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Online Access: | https://dspace.ncfu.ru/handle/20.500.12258/14216 |
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