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Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters

Cascade reaction of 2 equiv. of furfural (or equimolar amounts of furfural and aromatic aldehyde) with secondary amines and ethyl cyanoacetate afforded diethyl esters of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids with yields of 37–54%. Antimicrobial activity...

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Bibliographic Details
Main Authors: Dotsenko, V. V., Доценко, В. В.
Format: Статья
Language:English
Published: Pleiades journals 2020
Subjects:
Online Access:https://dspace.ncfu.ru/handle/20.500.12258/14216
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