Spirocyclic thienopyrimidines: synthesis, new rearrangement under vilsmeier conditions and in silico prediction of anticancer activity
Aim. To find novel anticancer lead molecules among easily available spiro-fused thieno[2,3-d] pyrimidines. Methods. Organic synthesis, spectral methods and molecular docking. Results. New spiro heterocycles were synthesized by condensation of 2-aminothiophene-3-carbonitriles with cyclic ketones via...
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| Médium: | Статья |
| Jazyk: | English |
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National Academy of Sciences of Ukraine
2020
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| On-line přístup: | https://dspace.ncfu.ru/handle/20.500.12258/14298 |
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