Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus

The item presents the results of a comparative immune enzymometric assay of the matrix metalloproteinases (MMP-1, MMP-2, MMP-8, MMP-9) and tissue inhibitors (TIMP-1, TIMP-2) levels in blood serum, oral fluid of children belonging to Health Groups I and II and children with type 1 diabetes mellitus (...

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Autors principals:	Anfinogenova, O. I., Анфиногенова, О. И., Glizhova, T. N., Глижова, Т. Н., Lysan, D. А., Лысань, Д. А., Nuzhnaya, C. V., Нужная, К. В.
Format:	Статья
Idioma:	English
Publicat:	EUROPAISCHE WISSENSCHAFTLICHE GESELLSCHAFT EV 2021
Matèries:	Child population Blood serum Oral fluid Ttissue inhibitors Matrix metalloproteinases Periodontal issues Type 1 diabetes mellitus
Accés en línia:	https://dspace.ncfu.ru/handle/20.500.12258/14839
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id	ir-20.500.12258-14839
record_format	dspace
spelling	ir-20.500.12258-148392021-01-26T14:45:02Z Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus Anfinogenova, O. I. Анфиногенова, О. И. Glizhova, T. N. Глижова, Т. Н. Lysan, D. А. Лысань, Д. А. Nuzhnaya, C. V. Нужная, К. В. Child population Blood serum Oral fluid Ttissue inhibitors Matrix metalloproteinases Periodontal issues Type 1 diabetes mellitus The item presents the results of a comparative immune enzymometric assay of the matrix metalloproteinases (MMP-1, MMP-2, MMP-8, MMP-9) and tissue inhibitors (TIMP-1, TIMP-2) levels in blood serum, oral fluid of children belonging to Health Groups I and II and children with type 1 diabetes mellitus (disease course within the range of 1 to 10 years) in projection onto the level of hygiene and the periodontal status. The role of MMP-2, MMP-8, MMP-9 in the pathogenetic mechanisms of inflammatory periodontal diseases development has been identified. Children with a short experience of endocrinopathy were found to have a balanced synthesis of matrix metalloproteinases and their tissue inhibitors in case of reversible inflammatory alterations in periodontal tissues. Children with a longer disease course were found to feature an imbalance between matrix metalloproteinases and tissue inhibitors, which provokes disturbances in remodeling and structural organization of the extracellular matrix in periodontal tissues, along with the development of inflammatory destructive issues 2021-01-26T14:43:49Z 2021-01-26T14:43:49Z 2019 Статья Domenyuk, D; Samedov, F; Dmitrienko, S; Anfinogenova, O; Glizhova, T; Lysan, D; Nuzhnaya, C. Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus // ARCHIV EUROMEDICA. - 2019. - Том: 9. - Выпуск: 3. - Стр.: 81-90 http://hdl.handle.net/20.500.12258/14839 en ARCHIV EUROMEDICA application/pdf EUROPAISCHE WISSENSCHAFTLICHE GESELLSCHAFT EV
institution	СКФУ
collection	Репозиторий
language	English
topic	Child population Blood serum Oral fluid Ttissue inhibitors Matrix metalloproteinases Periodontal issues Type 1 diabetes mellitus
spellingShingle	Child population Blood serum Oral fluid Ttissue inhibitors Matrix metalloproteinases Periodontal issues Type 1 diabetes mellitus Anfinogenova, O. I. Анфиногенова, О. И. Glizhova, T. N. Глижова, Т. Н. Lysan, D. А. Лысань, Д. А. Nuzhnaya, C. V. Нужная, К. В. Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus
description	The item presents the results of a comparative immune enzymometric assay of the matrix metalloproteinases (MMP-1, MMP-2, MMP-8, MMP-9) and tissue inhibitors (TIMP-1, TIMP-2) levels in blood serum, oral fluid of children belonging to Health Groups I and II and children with type 1 diabetes mellitus (disease course within the range of 1 to 10 years) in projection onto the level of hygiene and the periodontal status. The role of MMP-2, MMP-8, MMP-9 in the pathogenetic mechanisms of inflammatory periodontal diseases development has been identified. Children with a short experience of endocrinopathy were found to have a balanced synthesis of matrix metalloproteinases and their tissue inhibitors in case of reversible inflammatory alterations in periodontal tissues. Children with a longer disease course were found to feature an imbalance between matrix metalloproteinases and tissue inhibitors, which provokes disturbances in remodeling and structural organization of the extracellular matrix in periodontal tissues, along with the development of inflammatory destructive issues
format	Статья
author	Anfinogenova, O. I. Анфиногенова, О. И. Glizhova, T. N. Глижова, Т. Н. Lysan, D. А. Лысань, Д. А. Nuzhnaya, C. V. Нужная, К. В.
author_facet	Anfinogenova, O. I. Анфиногенова, О. И. Glizhova, T. N. Глижова, Т. Н. Lysan, D. А. Лысань, Д. А. Nuzhnaya, C. V. Нужная, К. В.
author_sort	Anfinogenova, O. I.
title	Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus
title_short	Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus
title_full	Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus
title_fullStr	Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus
title_full_unstemmed	Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus
title_sort	matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus
publisher	EUROPAISCHE WISSENSCHAFTLICHE GESELLSCHAFT EV
publishDate	2021
url	https://dspace.ncfu.ru/handle/20.500.12258/14839
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Matrix metalloproteinases and their tissue inhibitors in the pathogenesis of periodontal diseases in type 1 diabetes mellitus

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