Preparation of spiro[indole-3,5′-isoxazoles] via Grignard conjugate addition/spirocyclization sequence

A highly efficient one-pot procedure combining conjugate addition of Grignard reagents to (2-nitroalkenyl)indoles and sub-sequent Brønsted acid-assisted spirocyclization allowed for preparation of 4′H-spiro[indole-3,5′-isoxazoles] in a diastereomerically selective fashion. Utilization of alkyl Grign...

Full description

Saved in:

Bibliographic Details
Main Authors:	Aksenov, A. V., Аксенов, А. В., Aksenov, D. A., Аксенов, Д. А., Aksenov, N. A., Аксенов, Н. А., Skomorokhov, A. A., Скоморохов, А. А., Aleksandrova, E. V., Александрова, Е. В., Rubin, M. A., Рубин, М. А.
Format:	Статья
Language:	English
Published:	Royal Society of Chemistry 2021
Subjects:	Addition reactions Reagents Alkyl-substituted derivatives Polycyclic aromatic hydrocarbons
Online Access:	https://dspace.ncfu.ru/handle/20.500.12258/14853
Tags:	Add Tag No Tags, Be the first to tag this record!

Internet

https://dspace.ncfu.ru/handle/20.500.12258/14853

Preparation of spiro[indole-3,5′-isoxazoles] via Grignard conjugate addition/spirocyclization sequence

Internet

Similar Items