Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile

The reaction of (2E,4E)-5-phenyl-2-cyano-2,4-pentadienethioamide or (E)-3-(2-nitrophenyl)acrolein and cyanothioacetamide with alpha-bromoketones afforded new (2E,4E)-5-aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitriles. Direct bromination of the latter by the action of bromine in DMF proceeded regio...

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Auteurs principaux:	Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В., Shcherbakov, S. V., Щербаков, С. В., Ovcharov, S. N., Овчаров, С. Н.
Format:	Статья
Langue:	English
Publié:	MAIK NAUKA/INTERPERIODICA/SPRINGER 2021
Sujets:	Cyanothioacetamide 5-bromothiazoles Knoevenagel condensation (2E; 4E)-5-aryl-2-cyano-2 Bromination Hantzsch thiazole synthesis 4-pentadienethioamides
Accès en ligne:	https://dspace.ncfu.ru/handle/20.500.12258/15993
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record_format	dspace
spelling	ir-20.500.12258-159932021-06-10T12:14:04Z Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. Shcherbakov, S. V. Щербаков, С. В. Ovcharov, S. N. Овчаров, С. Н. Cyanothioacetamide 5-bromothiazoles Knoevenagel condensation (2E; 4E)-5-aryl-2-cyano-2 Bromination Hantzsch thiazole synthesis 4-pentadienethioamides The reaction of (2E,4E)-5-phenyl-2-cyano-2,4-pentadienethioamide or (E)-3-(2-nitrophenyl)acrolein and cyanothioacetamide with alpha-bromoketones afforded new (2E,4E)-5-aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitriles. Direct bromination of the latter by the action of bromine in DMF proceeded regiospecifically at the C-5 position of the thiazole ring without affecting the diene system and leads to the formation of new series of (2E,4E)-5-aryl-2-(5-bromo-4-arylthiazol-2-yl)penta-2,4-dienenitriles 2021-06-08T14:18:37Z 2021-06-08T14:18:37Z 2021 Статья Pakholka, NA; Dotsenko, VV; Krivokolysko, BS; Frolov, KA; Aksenov, NA; Aksenova, IV; Shcherbakov, SV ; Ovcharov, SN; Krivokolysko, SG. Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile // RUSSIAN JOURNAL OF GENERAL CHEMISTRY. - 2021. - Том: 91. - Выпуск: 4. - Стр.: 606-613 http://hdl.handle.net/20.500.12258/15993 en Russian Journal of General Chemistry application/pdf application/pdf MAIK NAUKA/INTERPERIODICA/SPRINGER
institution	СКФУ
collection	Репозиторий
language	English
topic	Cyanothioacetamide 5-bromothiazoles Knoevenagel condensation (2E; 4E)-5-aryl-2-cyano-2 Bromination Hantzsch thiazole synthesis 4-pentadienethioamides
spellingShingle	Cyanothioacetamide 5-bromothiazoles Knoevenagel condensation (2E; 4E)-5-aryl-2-cyano-2 Bromination Hantzsch thiazole synthesis 4-pentadienethioamides Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. Shcherbakov, S. V. Щербаков, С. В. Ovcharov, S. N. Овчаров, С. Н. Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
description	The reaction of (2E,4E)-5-phenyl-2-cyano-2,4-pentadienethioamide or (E)-3-(2-nitrophenyl)acrolein and cyanothioacetamide with alpha-bromoketones afforded new (2E,4E)-5-aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitriles. Direct bromination of the latter by the action of bromine in DMF proceeded regiospecifically at the C-5 position of the thiazole ring without affecting the diene system and leads to the formation of new series of (2E,4E)-5-aryl-2-(5-bromo-4-arylthiazol-2-yl)penta-2,4-dienenitriles
format	Статья
author	Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. Shcherbakov, S. V. Щербаков, С. В. Ovcharov, S. N. Овчаров, С. Н.
author_facet	Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. Shcherbakov, S. V. Щербаков, С. В. Ovcharov, S. N. Овчаров, С. Н.
author_sort	Dotsenko, V. V.
title	Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
title_short	Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
title_full	Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
title_fullStr	Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
title_full_unstemmed	Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
title_sort	synthesis and regiospecific bromination of (2e,4e)-5-aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
publisher	MAIK NAUKA/INTERPERIODICA/SPRINGER
publishDate	2021
url	https://dspace.ncfu.ru/handle/20.500.12258/15993
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Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile

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