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Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile

Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile

The reaction of (2E,4E)-5-phenyl-2-cyano-2,4-pentadienethioamide or (E)-3-(2-nitrophenyl)acrolein and cyanothioacetamide with alpha-bromoketones afforded new (2E,4E)-5-aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitriles. Direct bromination of the latter by the action of bromine in DMF proceeded regio...

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Bibliographic Details
Main Authors: Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В., Shcherbakov, S. V., Щербаков, С. В., Ovcharov, S. N., Овчаров, С. Н.
Format: Статья
Language:English
Published: MAIK NAUKA/INTERPERIODICA/SPRINGER 2021
Subjects:
Cyanothioacetamide
5-bromothiazoles
Knoevenagel condensation
(2E; 4E)-5-aryl-2-cyano-2
Bromination
Hantzsch thiazole synthesis
4-pentadienethioamides
Online Access:https://dspace.ncfu.ru/handle/20.500.12258/15993
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https://dspace.ncfu.ru/handle/20.500.12258/15993

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