Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes

The reaction of aromatic aldehydes with malononitrile, ethyl or butyl cyanoacetate and acetylacetone in the presence of NaOH under mild conditions (EtOH, 25 degrees C) led to the formation of new series of (1S,5R,6R,9R)/(1R,5S,6S,9S)-2-amino-6,9-diaryl-7-acetyl-8-methyl-4-oxo-5-cyano-3-azabicyclo[3....

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Asıl Yazarlar:	Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Materyal Türü:	Статья
Dil:	English
Baskı/Yayın Bilgisi:	MAIK NAUKA/INTERPERIODICA/SPRINGER 2021
Konular:	3-azabicyclo[3; 3; 1]nonane 2-amino-4H-pyrans Methylene active nitriles Cyanoacetic ester Multicomponent reactions (MCRs) Cascade reactions
Online Erişim:	https://dspace.ncfu.ru/handle/20.500.12258/16377
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id	ir-20.500.12258-16377
record_format	dspace
spelling	ir-20.500.12258-163772021-07-05T14:13:28Z Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. 3-azabicyclo[3; 3; 1]nonane 2-amino-4H-pyrans Methylene active nitriles Cyanoacetic ester Multicomponent reactions (MCRs) Cascade reactions The reaction of aromatic aldehydes with malononitrile, ethyl or butyl cyanoacetate and acetylacetone in the presence of NaOH under mild conditions (EtOH, 25 degrees C) led to the formation of new series of (1S,5R,6R,9R)/(1R,5S,6S,9S)-2-amino-6,9-diaryl-7-acetyl-8-methyl-4-oxo-5-cyano-3-azabicyclo[3.3.1]nona-2,7-diene-1-carboxylic acids esters. A plausible mechanism of the cascade reaction was proposed. 2021-07-02T12:17:03Z 2021-07-02T12:17:03Z 2021 Статья Ismiyev, AI; Dotsenko, VV; Aksenov, NA; Aksenova, IV; Magarramov, AM. Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes // RUSSIAN JOURNAL OF GENERAL CHEMISTRY. - 2021. - Том: 91. - Выпуск: 5. - Стр.: 758-767 http://hdl.handle.net/20.500.12258/16377 en Russian Journal of General Chemistry application/pdf application/pdf MAIK NAUKA/INTERPERIODICA/SPRINGER
institution	СКФУ
collection	Репозиторий
language	English
topic	3-azabicyclo[3; 3; 1]nonane 2-amino-4H-pyrans Methylene active nitriles Cyanoacetic ester Multicomponent reactions (MCRs) Cascade reactions
spellingShingle	3-azabicyclo[3; 3; 1]nonane 2-amino-4H-pyrans Methylene active nitriles Cyanoacetic ester Multicomponent reactions (MCRs) Cascade reactions Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes
description	The reaction of aromatic aldehydes with malononitrile, ethyl or butyl cyanoacetate and acetylacetone in the presence of NaOH under mild conditions (EtOH, 25 degrees C) led to the formation of new series of (1S,5R,6R,9R)/(1R,5S,6S,9S)-2-amino-6,9-diaryl-7-acetyl-8-methyl-4-oxo-5-cyano-3-azabicyclo[3.3.1]nona-2,7-diene-1-carboxylic acids esters. A plausible mechanism of the cascade reaction was proposed.
format	Статья
author	Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В.
author_facet	Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В.
author_sort	Dotsenko, V. V.
title	Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes
title_short	Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes
title_full	Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes
title_fullStr	Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes
title_full_unstemmed	Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes
title_sort	pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes
publisher	MAIK NAUKA/INTERPERIODICA/SPRINGER
publishDate	2021
url	https://dspace.ncfu.ru/handle/20.500.12258/16377
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Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes

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