Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes

Pseudo-five-component stereoselective synthesis of highly functionalized 3-azabicyclo[3.3.1]nona-2,7-dienes

The reaction of aromatic aldehydes with malononitrile, ethyl or butyl cyanoacetate and acetylacetone in the presence of NaOH under mild conditions (EtOH, 25 degrees C) led to the formation of new series of (1S,5R,6R,9R)/(1R,5S,6S,9S)-2-amino-6,9-diaryl-7-acetyl-8-methyl-4-oxo-5-cyano-3-azabicyclo[3....

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Dettagli Bibliografici
Autori principali:	Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Natura:	Статья
Lingua:	English
Pubblicazione:	MAIK NAUKA/INTERPERIODICA/SPRINGER 2021
Soggetti:	3-azabicyclo[3; 3; 1]nonane 2-amino-4H-pyrans Methylene active nitriles Cyanoacetic ester Multicomponent reactions (MCRs) Cascade reactions
Accesso online:	https://dspace.ncfu.ru/handle/20.500.12258/16377
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne! !

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