Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds
The efficiency assessment of nanosized zinc oxide (ZnO) as a component of a high-potency wound-healing ointment composition was performed. The ointment consisted of a hydrophilic methylcellulose base and 5 wt. % ZnO nanoparticles as an active substance. Nanosized ZnO was obtained by the sol-gel meth...
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Stavropol State Medical University
2021
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ir-20.500.12258-180752021-09-03T12:20:30Z Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds Blinov, A. V. Блинов, А. В. Blinova, A. A. Блинова, А. А. Serov, A. V. Серов, А. В. Zinc oxide nanoparticles Wound healing Burn injuries Ointment Regenerative effect X ray powder diffraction The efficiency assessment of nanosized zinc oxide (ZnO) as a component of a high-potency wound-healing ointment composition was performed. The ointment consisted of a hydrophilic methylcellulose base and 5 wt. % ZnO nanoparticles as an active substance. Nanosized ZnO was obtained by the sol-gel method. Commercial zinc ointment was used as a comparison sample. Planimetric studies were conducted on the effectiveness of burn-wound healing in white Wistar rats. Three cases were considered: wounds were treated using a pharmaceutical zinc ointment or the ointment with ZnO nanoparticles, or received no treatment. Histological studies of the effectiveness of wound healing on treatment with the ointment containing ZnO nanoparticles were also performed. The ointment with the nanosized ZnO-based composition based had a pronounced regenerative effect on burn wounds. Its effect was greater than that of the existing analog – pharmaceutical zinc ointment 2021-09-03T12:18:40Z 2021-09-03T12:18:40Z 2021 Статья Elbekyan, K. S.; Blinov, A. V.; Blinova, A. A .; Fedota N. V.; Orobets, V. A.; Serov, A. V. Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds // Medical News of North Caucasus. 2021. - Том 16.- Выпуск 2. - Стр.: 194 - 199 http://hdl.handle.net/20.500.12258/18075 en Medical News of North Caucasus application/pdf Stavropol State Medical University |
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English |
topic |
Zinc oxide nanoparticles Wound healing Burn injuries Ointment Regenerative effect X ray powder diffraction |
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Zinc oxide nanoparticles Wound healing Burn injuries Ointment Regenerative effect X ray powder diffraction Blinov, A. V. Блинов, А. В. Blinova, A. A. Блинова, А. А. Serov, A. V. Серов, А. В. Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds |
description |
The efficiency assessment of nanosized zinc oxide (ZnO) as a component of a high-potency wound-healing ointment composition was performed. The ointment consisted of a hydrophilic methylcellulose base and 5 wt. % ZnO nanoparticles as an active substance. Nanosized ZnO was obtained by the sol-gel method. Commercial zinc ointment was used as a comparison sample. Planimetric studies were conducted on the effectiveness of burn-wound healing in white Wistar rats. Three cases were considered: wounds were treated using a pharmaceutical zinc ointment or the ointment with ZnO nanoparticles, or received no treatment. Histological studies of the effectiveness of wound healing on treatment with the ointment containing ZnO nanoparticles were also performed. The ointment with the nanosized ZnO-based composition based had a pronounced regenerative effect on burn wounds. Its effect was greater than that of the existing analog – pharmaceutical zinc ointment |
format |
Статья |
author |
Blinov, A. V. Блинов, А. В. Blinova, A. A. Блинова, А. А. Serov, A. V. Серов, А. В. |
author_facet |
Blinov, A. V. Блинов, А. В. Blinova, A. A. Блинова, А. А. Serov, A. V. Серов, А. В. |
author_sort |
Blinov, A. V. |
title |
Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds |
title_short |
Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds |
title_full |
Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds |
title_fullStr |
Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds |
title_full_unstemmed |
Practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds |
title_sort |
practical application of efficiency estimation of nanosized zinc oxide in the therapy of burn wounds |
publisher |
Stavropol State Medical University |
publishDate |
2021 |
url |
https://dspace.ncfu.ru/handle/20.500.12258/18075 |
work_keys_str_mv |
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