[3 + 2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor

Indolizines and pyrazolo[1,5-a]pyridines were prepared via [3 + 2]-cycloaddition of pyridinium ylides to 1-chloro-2-nitrostyrenes. The synthesized molecules were evaluated for antiproliferative activities against a BE(2)-C neuroblastoma cell line with several compounds decreasing the viability of ca...

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Principais autores:	Aksenov, A. V., Аксенов, А. В., Arutiunov, N. A., Арутюнов, Н. А., Kirilov, N. K., Кирилов, Н. К., Aksenov, D. A., Аксенов, Д. А., Grishin, I. Y., Гришин, И. Ю., Aksenov, N. A., Аксенов, Н. А., Rubin, M. A., Рубин, М. А.
Formato:	Статья
Idioma:	English
Publicado em:	Royal Society of Chemistry 2021
Assuntos:	Indolizines Pyrazolo[1,5-a]pyridines Indolizine 9db Anticancer agents
Acesso em linha:	https://dspace.ncfu.ru/handle/20.500.12258/18098
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https://dspace.ncfu.ru/handle/20.500.12258/18098

[3 + 2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor

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