2-Amino-4,5-dihydrothiophene-3-carbonitriles: A New Synthesis, Quantum Chemical Studies, and Mannich-Type Reactions Leading to New Hexahydrothieno[2,3-d]pyrimidines
trans-2-Amino-4-aryl-5-benzoyl-4,5-dihydrothiophene-3-carbonitriles were prepared either by the reaction of 3-aryl-2-cyanothioacrylamides with α-thiocyanatoacetophenone or by the Michael-type addition of cyanothioacetamide to α-bromochalcones followed by intramolecular cyclization. The mechanism of...
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| Main Authors: | , , , , , |
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| Format: | Статья |
| Language: | English |
| Published: |
American Chemical Society
2021
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| Subjects: | |
| Online Access: | https://dspace.ncfu.ru/handle/20.500.12258/18471 |
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