An efficient approach to 2-CF3-indoles based on ortho-nitrobenzaldehydes

An efficient approach to 2-CF3-indoles based on ortho-nitrobenzaldehydes

The catalytic olefination reaction of 2-nitrobenzaldehydes with CF3 CCl3 afforded stereose-lectively trifluoromethylated ortho-nitrostyrenes in up to 88% yield. The reaction of these alkenes with pyrrolidine permits preparation of α-CF3-β-(2-nitroaryl) enamines. Subsequent one pot reduction of nitro...

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Главные авторы:	Abaev, V. T., Абаев, В. Т.
Формат:	Статья
Язык:	English
Опубликовано:	MDPI 2021
Темы:	Indole Reduction Catalytic olefination reaction CF3-group Fluorine Nitro group
Online-ссылка:	https://dspace.ncfu.ru/handle/20.500.12258/18555
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