An efficient approach to 2-CF3-indoles based on ortho-nitrobenzaldehydes
The catalytic olefination reaction of 2-nitrobenzaldehydes with CF3 CCl3 afforded stereose-lectively trifluoromethylated ortho-nitrostyrenes in up to 88% yield. The reaction of these alkenes with pyrrolidine permits preparation of α-CF3-β-(2-nitroaryl) enamines. Subsequent one pot reduction of nitro...
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| Главные авторы: | , |
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| Formato: | Статья |
| Idioma: | English |
| Publicado: |
MDPI
2021
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| Темы: | |
| Acceso en liña: | https://dspace.ncfu.ru/handle/20.500.12258/18555 |
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