Ultrasonic-treated fucoidan as a promising therapeutic agent

Fucoidans represent the sulfated heteropolysaccharides that possess a wide range of important pharmacological properties. The properties of a fucoidan depend on several factors, including the molecular weight and the way of extraction. However, the selection of an optimal depolymerization method is...

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Egile Nagusiak:	Suprunchuk, V. E., Супрунчук, В. Е.
Formatua:	Статья
Hizkuntza:	English
Argitaratua:	NLM (Medline) 2022
Gaiak:	Antioxidant activity Ultrasonic treatment Depolymerization Fucoidan Ultrasonic extraction Molecular weight
Sarrera elektronikoa:	https://dspace.ncfu.ru/handle/20.500.12258/18602
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id	ir-20.500.12258-18602
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spelling	ir-20.500.12258-186022022-01-24T07:44:44Z Ultrasonic-treated fucoidan as a promising therapeutic agent Suprunchuk, V. E. Супрунчук, В. Е. Antioxidant activity Ultrasonic treatment Depolymerization Fucoidan Ultrasonic extraction Molecular weight Fucoidans represent the sulfated heteropolysaccharides that possess a wide range of important pharmacological properties. The properties of a fucoidan depend on several factors, including the molecular weight and the way of extraction. However, the selection of an optimal depolymerization method is necessary to enhance its therapeutic applications. Reducing the molecular weight of fucoidans will make it possible to use them in creating nanoparticles and nanocarriers for, among others, the targeted drug delivery. The molecular mass of the polymer can be changed by means of various methods of depolymerization. In this work, the possibility of application of ultrasonic destruction for decrease in the size of fucoidan molecules for the purpose of expansion of opportunities and spheres of their therapeutic application is considered. This is one of the simple and effective methods of depolymerization of fucoidan, which leads to a decrease in molecular weight without significant structural changes in macromolecules. In addition, methods and potential applications of the ultrasonic extraction of fucoidan from seaweed and the possibilities of their combination are discussed, as well as other physical or chemical methods of extraction. 2022-01-24T07:43:46Z 2022-01-24T07:43:46Z 2021 Статья Suprunchuk, V. E. Ultrasonic-treated fucoidan as a promising therapeutic agent // Polimery w medycynie. - 2021. - Том 51. - Выпуск 2. - Стр.: 85 - 90. - DOI10.17219/pim/143961 http://hdl.handle.net/20.500.12258/18602 en Polimery w medycynie application/pdf NLM (Medline)
institution	СКФУ
collection	Репозиторий
language	English
topic	Antioxidant activity Ultrasonic treatment Depolymerization Fucoidan Ultrasonic extraction Molecular weight
spellingShingle	Antioxidant activity Ultrasonic treatment Depolymerization Fucoidan Ultrasonic extraction Molecular weight Suprunchuk, V. E. Супрунчук, В. Е. Ultrasonic-treated fucoidan as a promising therapeutic agent
description	Fucoidans represent the sulfated heteropolysaccharides that possess a wide range of important pharmacological properties. The properties of a fucoidan depend on several factors, including the molecular weight and the way of extraction. However, the selection of an optimal depolymerization method is necessary to enhance its therapeutic applications. Reducing the molecular weight of fucoidans will make it possible to use them in creating nanoparticles and nanocarriers for, among others, the targeted drug delivery. The molecular mass of the polymer can be changed by means of various methods of depolymerization. In this work, the possibility of application of ultrasonic destruction for decrease in the size of fucoidan molecules for the purpose of expansion of opportunities and spheres of their therapeutic application is considered. This is one of the simple and effective methods of depolymerization of fucoidan, which leads to a decrease in molecular weight without significant structural changes in macromolecules. In addition, methods and potential applications of the ultrasonic extraction of fucoidan from seaweed and the possibilities of their combination are discussed, as well as other physical or chemical methods of extraction.
format	Статья
author	Suprunchuk, V. E. Супрунчук, В. Е.
author_facet	Suprunchuk, V. E. Супрунчук, В. Е.
author_sort	Suprunchuk, V. E.
title	Ultrasonic-treated fucoidan as a promising therapeutic agent
title_short	Ultrasonic-treated fucoidan as a promising therapeutic agent
title_full	Ultrasonic-treated fucoidan as a promising therapeutic agent
title_fullStr	Ultrasonic-treated fucoidan as a promising therapeutic agent
title_full_unstemmed	Ultrasonic-treated fucoidan as a promising therapeutic agent
title_sort	ultrasonic-treated fucoidan as a promising therapeutic agent
publisher	NLM (Medline)
publishDate	2022
url	https://dspace.ncfu.ru/handle/20.500.12258/18602
work_keys_str_mv	AT suprunchukve ultrasonictreatedfucoidanasapromisingtherapeuticagent AT suprunčukve ultrasonictreatedfucoidanasapromisingtherapeuticagent
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Ultrasonic-treated fucoidan as a promising therapeutic agent

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