Electrophilically activated nitroalkanes in the synthesis of substituted 1,3,4-oxadiazoles from amino acid derivatives
Novel preparative approach for the synthesis of alkylamines with 1,3,4-oxadiazole heterocyclic substituent is described. This method is based on unusual cascade transformation involving formal (4+1) cyclocondensation of hydrazides of amino acids with nitroalkanes electrophilically activated in the p...
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| Glavni autori: | , , , , , , , , , , , |
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| Format: | Статья |
| Jezik: | English |
| Izdano: |
Springer
2022
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| Teme: | |
| Online pristup: | https://dspace.ncfu.ru/handle/20.500.12258/18827 |
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| Sažetak: | Novel preparative approach for the synthesis of alkylamines with 1,3,4-oxadiazole heterocyclic substituent is described. This method is based on unusual cascade transformation involving formal (4+1) cyclocondensation of hydrazides of amino acids with nitroalkanes electrophilically activated in the presence of polyphosphoric acid. |
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