Investigation of cationic transformations involving 5-ethynyl-4-arylpyrimidines

Investigation of cationic transformations involving 5-ethynyl-4-arylpyrimidines

An innovative synthetic approach towards 5-ethynyl-4-arylpyrimidines was developed involving acid-catalyzed electrophilic alkylation of phenols with 5-bromopyrimidine, followed by oxidation and palladium-catalyzed Sonogashira cross-coupling reaction. Reactions of these compounds in the presence of t...

Полное описание

Сохранить в:

Библиографические подробности
Главные авторы:	Shcherbakov, S. V., Щербаков, С. В., Magometov, A. Y., Магометов, А. Ю., Vendin, M. V., Вендин, М. В., Shcherbakova, V. Y., Щербакова, В. Ю., Aksenov, N. A., Аксенов, Н. А., Aksenov, A. V., Аксенов, А. В., Rubin, M. A., Рубин, М. А.
Формат:	Статья
Язык:	English
Опубликовано:	Elsevier Ltd 2022
Темы:	Acetylenes Cationic rearrangements Heterocyclic chemistry Reaction mechanisms Synthetic methodology
Online-ссылка:	https://dspace.ncfu.ru/handle/20.500.12258/19633
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!

Схожие документы

Electrophilic iodonium-ion mediated spirocyclization of 4-(5-(arylethynyl)pyrimidin-4-yl)phenols enroute to spiro[cyclohexa[2,5]diene-1,7′-cyclopenta[d]pyrimidin]-4-one core
Автор: Arutiunov, N. A., и др.
Опубликовано: (2025)

Reaction of tetra(phenylethynyl)tin with aromatic aldehydes: a new one-pot method for the synthesis of α-acetylene ketones
Автор: Dotsenko, V. V., и др.
Опубликовано: (2020)

Synthetic studies towards benzofuro[2,3-b]quinoline and 6H-indolo[2,3-b]quinoline cores: Total synthesis of norneocryptolepine and neocryptolepine
Автор: Aksenov, D. A., и др.
Опубликовано: (2021)

Synthesis of 2,4-Disubstituted Quinolines by the Reaction of Propargylic Alcohols with Anilines in a Polyphosphoric Acid Medium
Автор: Aksenov, A. V., и др.
Опубликовано: (2025)

Direct conversion of 3-(2-nitroethyl)-1H-indoles into 2-(1H-indol-2-yl)acetonitriles
Автор: Aksenov, A. V., и др.
Опубликовано: (2021)

Improved method for preparation of 3-(1H-Indol-3-yl)benzofuran-2(3H)-ones
Автор: Grishin, I. Y., и др.
Опубликовано: (2022)

Novel Two-Step Synthesis of N -Alkylated 2,3-Diaryl-4-quinolones
Автор: Aksenov, A. V., и др.
Опубликовано: (2024)

One-pot synthesis of 4-methyl-2-alkyl quinazoline-N-oxides by cascade acetamidation–acylation of simple electron-rich arenes with primary nitroalkanes
Автор: Grishin, I. Y., и др.
Опубликовано: (2025)

One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-Ylidene)-2-Arylacetonitriles
Автор: Aksenov, N. A., и др.
Опубликовано: (2022)

Synthesis and structure of new 2,4-dicyano-6-oxo-3-phenylbicyclo[3.2.1]octane-2,4-dicarboxylates
Автор: Dotsenko, V. V., и др.
Опубликовано: (2020)

One-pot synthesis of substituted quinolines and 3,3′-(arylmethylene)bis(1H-indoles) via a metal-free polyphosphoric acid-mediated acetylene hydrolysis strategy
Автор: Arutiunov, N. A., и др.
Опубликовано: (2025)

New photochromic indoline spiropyrans containing cationic substituent in the 2H-chromene moiety
Автор: Aksenov, N. A., и др.
Опубликовано: (2018)

Does electrophilic activation of nitroalkanes in polyphosphoric acid involve formation of nitrile oxides?
Автор: Aksenov, A. V., и др.
Опубликовано: (2021)

Synthesis of new hyperbranched dendrimers with terminal cationic groups based on boltorn H20 polyester polyol
Автор: Dotsenko, V. V., и др.
Опубликовано: (2020)

Photo- and ionochromic N-acylated 2-(aminomethylene)benzo[b]thiophene-3(2H)-ones containing a terpyridine receptor
Автор: Demidov, O. P., и др.
Опубликовано: (2025)

INVOLVEMENT OF THE ENDOCANNABINOID SYSTEM IN ADDICTIVE BEHAVIOR Статья
Автор: Rafael M. L.

Oxidation of 2-(5-bromo-3,4-dihydropyrimidin-4-yl)phenols, a new approach to the synthesis of benzofuro[3,2-d]pyrimidines
Автор: Shcherbakov, S. V., и др.
Опубликовано: (2023)

Synthesis of chromenoimidazocarbolines by a reaction of quaternary iminium salts with o-hydroxybenzaldehydes
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Reaction of benzyne with 1,2,3,4-tetrahydroisoquinolines as an access to 1H-3-benzazepines
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Reactions of 3,4-dihydroisoquinolines and dihydrothieno[3,2-c]pyridines with benzyne
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Domino reactions of 1-substituted N-(cyanomethyl)isoquinolinium salts with salicylic aldehydes
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Mn-mediated sequential three-component domino Knoevenagel/cyclization/Michael addition/oxidative cyclization reaction towards annulated imidazo[1,2-a]pyridines
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)

A facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Interaction of condensed tetrahydropyrido[4,3-d]pyrimidin-4-ones with dehydrobenzene – synthesis of 6-vinylpyrimidinones fused with five-membered heterocycle containing two or three heteroatoms
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Three-component reaction of ketals, isonitriles, and trimethylsilyl azide
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

A novel multi-component approach to the synthesis of pyrrolo[2,1-a] isoquinoline derivatives
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

First synthesis of heterocyclic allenes-benzazecine derivatives
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Synthesis and investigation of nanoscale magnesium carbonate stabilized with hyaluronic acid
Автор: Blinov, A. V., и др.
Опубликовано: (2025)

Introduction of tetrazol-1-yl and 5-methyltetrazol-1-yl substituents in the phenyl ring of dibenzo-18-crown-6
Автор: Aksenov, N. A., и др.
Опубликовано: (2018)

Modern trends of organic chemistry in russian universities
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Betti reaction of 2-naphthol, furfural, and acetamide: an unexpected case of secondary carbo-Piancatelli rearrangement
Автор: Demidov, O. P., и др.
Опубликовано: (2019)

Investigation of the process of polymer stabilization of mixed iron oxide with amylopectin
Автор: Nagdalian, A. A., и др.
Опубликовано: (2025)

Organic Chemistry in Russian Universities. Achievements of Recent Years
Автор: Aksenov, D. A., и др.
Опубликовано: (2024)

Investigation of the Effect of the Type of Precursor and Precipitator on the Structure of Nanoscale Magnesium Carbonate
Автор: Blinov, A. V., и др.
Опубликовано: (2025)

Synthesis of 3,4-dihydroisoquinolines using nitroalkanes in polyphosphoric acid
Автор: Aksenov, N. A., и др.
Опубликовано: (2019)

The chemistry of heterocycles in the 21st century
Автор: Dotsenko, V. V., и др.
Опубликовано: (2024)

Catastrophes and serviceability of reinforced concrete structures (Classifi cation and elements of theory) мonograph
Автор: Skorobogatov S. M.
Опубликовано: (2020)

Investigation of the Rank of Numbers Represented in the Residue Number System
Автор: Kuchukov, V. A., и др.
Опубликовано: (2024)

A new series of acetohydroxamates shows in vitro and in vivo anticancer activity against melanoma
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)