Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N

Unusual cascade transformation was developed involving microwave assisted electrocyclic cyclization of aci (alkylideneazinic acid) forms of nitrovinylindoles acting as heterotrienes. Subsequent one-pot reduction allowed for efficient access to β-carbolines, including several natural products, alkalo...

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Главные авторы:	Aksenov, N. A., Аксенов, Н. А., Arutiunov, N. A., Арутюнов, Н. А., Aksenov, A. V., Аксенов, А. В., Aksenova, I. V., Аксенова, И. В., Aleksandrova, E. V., Александрова, Е. В., Aksenov, D. A., Аксенов, Д. А., Rubin, M. A., Рубин, М. А.
Формат:	Статья
Язык:	English
Опубликовано:	American Chemical Society 2022
Темы:	Alkaloids Biological products Carbolines Cyclization Harmine
Online-ссылка:	https://dspace.ncfu.ru/handle/20.500.12258/21932
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spelling	ir-20.500.12258-219322025-02-13T12:28:26Z Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N Aksenov, N. A. Аксенов, Н. А. Arutiunov, N. A. Арутюнов, Н. А. Aksenov, A. V. Аксенов, А. В. Aksenova, I. V. Аксенова, И. В. Aleksandrova, E. V. Александрова, Е. В. Aksenov, D. A. Аксенов, Д. А. Rubin, M. A. Рубин, М. А. Alkaloids Biological products Carbolines Cyclization Harmine Unusual cascade transformation was developed involving microwave assisted electrocyclic cyclization of aci (alkylideneazinic acid) forms of nitrovinylindoles acting as heterotrienes. Subsequent one-pot reduction allowed for efficient access to β-carbolines, including several natural products, alkaloids norharmane, harmane and eudistomin N. 2022-12-06T12:19:22Z 2022-12-06T12:19:22Z 2022 Статья Aksenov, N.A., Arutiunov, N.A., Aksenov, A.V., Aksenova, I.V., Aleksandrova, E.V., Aksenov, D.A., Rubin, M. Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N // Organic Letters. - 2022. - Volume 24. - Issue 39. - Pages 7062-7066. - DOI10.1021/acs.orglett.2c02483 http://hdl.handle.net/20.500.12258/21932 en Organic Letters application/pdf application/pdf American Chemical Society
institution	СКФУ
collection	Репозиторий
language	English
topic	Alkaloids Biological products Carbolines Cyclization Harmine
spellingShingle	Alkaloids Biological products Carbolines Cyclization Harmine Aksenov, N. A. Аксенов, Н. А. Arutiunov, N. A. Арутюнов, Н. А. Aksenov, A. V. Аксенов, А. В. Aksenova, I. V. Аксенова, И. В. Aleksandrova, E. V. Александрова, Е. В. Aksenov, D. A. Аксенов, Д. А. Rubin, M. A. Рубин, М. А. Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N
description	Unusual cascade transformation was developed involving microwave assisted electrocyclic cyclization of aci (alkylideneazinic acid) forms of nitrovinylindoles acting as heterotrienes. Subsequent one-pot reduction allowed for efficient access to β-carbolines, including several natural products, alkaloids norharmane, harmane and eudistomin N.
format	Статья
author	Aksenov, N. A. Аксенов, Н. А. Arutiunov, N. A. Арутюнов, Н. А. Aksenov, A. V. Аксенов, А. В. Aksenova, I. V. Аксенова, И. В. Aleksandrova, E. V. Александрова, Е. В. Aksenov, D. A. Аксенов, Д. А. Rubin, M. A. Рубин, М. А.
author_facet	Aksenov, N. A. Аксенов, Н. А. Arutiunov, N. A. Арутюнов, Н. А. Aksenov, A. V. Аксенов, А. В. Aksenova, I. V. Аксенова, И. В. Aleksandrova, E. V. Александрова, Е. В. Aksenov, D. A. Аксенов, Д. А. Rubin, M. A. Рубин, М. А.
author_sort	Aksenov, N. A.
title	Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N
title_short	Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N
title_full	Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N
title_fullStr	Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N
title_full_unstemmed	Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N
title_sort	nitrovinylindoles as heterotrienes: electrocyclic cyclization en route to β-carbolines: total synthesis of alkaloids norharmane, harmane, and eudistomin n
publisher	American Chemical Society
publishDate	2022
url	https://dspace.ncfu.ru/handle/20.500.12258/21932
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Nitrovinylindoles as Heterotrienes: Electrocyclic Cyclization En Route to β-Carbolines: Total Synthesis of Alkaloids Norharmane, Harmane, and Eudistomin N

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