Oxidation of 2-Cyanothioacrylamides with Sodium Nitrite in Acidic Medium

Oxidation of 2-Cyanothioacrylamides with Sodium Nitrite in Acidic Medium

(E)-3-Aryl-2-cyanoprop-2-entioamides, prepared by Knoevenagel condensation between aromatic aldehydes and cyanothioacetamide, react with sodium nitrite in acetic acid to form (2E,2′E)-2,2′-(1,2,4-thiadiazole-3,5-diyl)bis[3-arylacrylonitriles]. A possible mechanism and limitations of the reaction are...

Uloženo v:

Podrobná bibliografie
Hlavní autoři:	Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В., Likhovid, N. G., Лиховид, Н. Г.
Médium:	Статья
Jazyk:	English
Vydáno:	Pleiades journals 2022
Témata:	1,2,4-thiadiazoles 2-cyanothioacrylamides Cyanothioacetamide Oxidative dimerization Thioamides
On-line přístup:	https://dspace.ncfu.ru/handle/20.500.12258/21940
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky

(2E,2′E)-2,2′-(1,2,4-Thiadiazole-3,5-diyl)bis[3-arylacrylonitriles]: Synthesis and Antidote Activity Towards 2,4-D Herbicide
Autor: Dotsenko, V. V., a další
Vydáno: (2023)

Electrochemical Oxidation of 3-Aryl-2-cyanothioacrylamides
Autor: Dotsenko, V. V., a další
Vydáno: (2023)

Oxidation of 4,6-Dimethyl-2-thioxo-1,2-dihydropyridine-3-carbonitriles with Potassium Ferricyanide: Synthesis and Molecular Docking of Bis(pyrid-2-yl) Disulfides
Autor: Dotsenko, V. V., a další
Vydáno: (2024)

Synthesis and Structure of (2E)-3-Aryl(hetaryl)-2-[5-bromo-4-aryl(hetaryl)-1,3-thiazol-2-yl]acrylonitriles
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

Reaction of thieno[2,3-b]pyridines with sodium hypochlorite: An unusual and stereoselective one-pot approach to dimeric pyrrolo[2′,3′:4,5]thieno[2,3-b]pyridines
Autor: Dotsenko, V. V., a další
Vydáno: (2019)

Synthesis and Aminomethylation of 6-Amino-2-(dicyanomethylene)-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile Morpholinium Salt
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

N-Hydroxymethylation of 3-Aryl-2-cyanoprop-2-enethioamides
Autor: Dotsenko, V. V., a další
Vydáno: (2020)

Synthesis of derivatives of a novel heterocyclic system 7-thia-1,4,6,8-tetraazabenzo[de]anthracene
Autor: Dotsenko, V. V., a další
Vydáno: (2018)

Synthesis of derivatives of a novel heterocyclic system 7-thia-1,4,6,8-tetraazabenzo[de]anthracene
Autor: Dotsenko, V. V., a další
Vydáno: (2018)

Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

1,6-Diamino-2-oxopyridine-3,5-dicarbonitrile Derivatives in the Mannich Reaction
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity
Autor: Dotsenko, V. V., a další
Vydáno: (2022)

Recent advances in the chemistry of thieno[2,3-b]pyridines 1. Methods of synthesis of thieno[2,3-b]pyridines
Autor: Dotsenko, V. V., a další
Vydáno: (2020)

Synthesis and analgesic activity of new heterocyclic cyanothioacetamide derivatives
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

Synthesis and properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines
Autor: Dotsenko, V. V., a další
Vydáno: (2019)

Reaction of N,N′-Diphenyldithiomalondiamide with Aromatic Aldehydes and Cyanoacetamide
Autor: Dotsenko, V. V., a další
Vydáno: (2023)

Synthesis of 4,6-disubstituted 2-thioxo-1,2-dihydropyridine-3-carbonitriles by the reaction of acetylenic ketones with cyanothioacetamide
Autor: Dotsenko, V. V., a další
Vydáno: (2019)

Synthesis and Aminomethylation of 2-Amino-4-(2-chlorophenyl)-6-(dicyanomethyl)-1,4-dihydropyridine-3,5-dicarbonitrile N-Methylmorpholinium Salt
Autor: Dotsenko, V. V., a další
Vydáno: (2022)

A new Approach to the synthesis of functional derivatives of 3-(4-Pyridinyl)-1H-indole and 4-s(1H-Indol-3-yl)thieno[2,3-b]pyridine
Autor: Dotsenko, V. V., a další
Vydáno: (2018)

Synthesis and In vivo Evaluation of Hepatoprotective Effects of Novel Sulfur-Containing 1,4-Dihydropyridines and 1,2,3,4-Tetrahydropyridines
Autor: Dotsenko, V. V., a další
Vydáno: (2023)

Alkyl 4-Aryl-6-amino-7- phenyl-3-(phenylimino)-4,7-dihydro- 3H-[1,2]dithiolo[3,4-b]pyridine-5-carboxylates: Synthesis and Agrochemical Studies
Autor: Dotsenko, V. V., a další
Vydáno: (2023)

Synthesis and research of nanocompositions of oxide materials based on titanium dioxide for use as contrast agents in optical coherence tomography
Autor: Povetkin, S. N., a další
Vydáno: (2021)

New Heterocyclization Reactions with Malononitrile Dimer
Autor: Dotsenko, V. V., a další
Vydáno: (2024)

Synthesis and properties of new fluorine-containing thieno[2,3-b]pyridine derivatives
Autor: Dotsenko, V. V., a další
Vydáno: (2019)

Unusual cyclization of N-imidazolyl quinone imines with the formation of thiadiazole ring and its subsequent recyclization
Autor: Demidov, O. P., a další
Vydáno: (2022)

Mn-mediated sequential three-component domino Knoevenagel/cyclization/Michael addition/oxidative cyclization reaction towards annulated imidazo[1,2-a]pyridines
Autor: Aksenov, A. V., a další
Vydáno: (2019)

Synthesis and some properties of new 5-Hydroxy-2-[(hetarylthio)methyl]-4H-pyran-4-ones
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

First Synthesis of 2-Amino-5-hydroxy-4H-chromene-3-carbonitriles from 4-(2-Pyridylazo)resorcinol
Autor: Dotsenko, V. V., a další
Vydáno: (2023)

Mannich Reaction Involving 6-Amino-4-methyl-2-(thio)oxo-1,2-dihydropyridine-3,5-dicarbonitriles
Autor: Strelkov, V. D., a další
Vydáno: (2023)

Reactions of malononitrile dimer with isothiocyanates
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

N,N′-Diphenyldithiomalonodiamide: structural features, acidic properties, and in silico estimation of biological activity
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

Unexpected result of thiophosphorylation of 6-aminopyrano[2,3-c]pyrazole-5-carbonitrile derivative
Autor: Dotsenko, V. V., a další
Vydáno: (2019)

Synthesis, structure, and analgesic activity of 4-(5-Cyano-{4-(fur-2-yl)-1,4-dihydropyridin-3-yl}carboxamido)benzoic acids ethyl esters
Autor: Dotsenko, V. V., a další
Vydáno: (2022)

Synthesis of new polycyclic compounds containing thieno[2′,3′:5,6]pyrimido[2,1-a]isoindole fragment
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

Histological studies of organs in experiment on the application of a niosomal form of anti-tumor medicine
Autor: Aksenov, A. V., a další
Vydáno: (2020)

Reaction of 3-Amino-4,6-diarylthieno[2,3-b]pyridine-2-carboxamides with Ninhydrin
Autor: Dotsenko, V. V., a další
Vydáno: (2020)

Methylene Components Exchange in the Reaction of Cyanoacetohydrazide with 2-Amino-4-arylbuta-1,3-diene-1,1,3-tricarbonitriles
Autor: Dotsenko, V. V., a další
Vydáno: (2021)

Synthesis of thiazolo[3,2-a]pyridines via an unusual Mannich-type cyclization
Autor: Dotsenko, V. V., a další
Vydáno: (2018)

Synthesis and biological activity of 8-(dialkylamino)-3-aryl-6-oxo-2,4-dicyanobicyclo[3.2.1]octane-2,4-dicarboxylic acids diethyl esters
Autor: Dotsenko, V. V., a další
Vydáno: (2020)

Synthesis and Cyclizations of N-(Thieno[2,3-b]pyridin-3-yl)cyanoacetamides
Autor: Dotsenko, V. V., a další
Vydáno: (2019)