α-Amino acid-assisted autoxidation of naphthalene proton sponge affording 1,4-naphthoquinone nitrogen derivatives
1,8-Bis(dimethylamino)naphthalene (naphthalene proton sponge) equipped at position 4 with N-terminal α-amino acid residues undergoes unprecedented easy autoxidation in basic medium forming 5-dimethylamino-1,4-naphthoquinone along with minor amounts of its derivatives. The new reaction is of interest...
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| Auteurs principaux: | , |
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| Format: | Статья |
| Langue: | English |
| Publié: |
2023
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| Sujets: | |
| Accès en ligne: | https://dspace.ncfu.ru/handle/20.500.12258/23793 |
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| Résumé: | 1,8-Bis(dimethylamino)naphthalene (naphthalene proton sponge) equipped at position 4 with N-terminal α-amino acid residues undergoes unprecedented easy autoxidation in basic medium forming 5-dimethylamino-1,4-naphthoquinone along with minor amounts of its derivatives. The new reaction is of interest against the background of wide distribution of 1,4-naphthoquinones in nature, their high biological significance and extremely limited information on nitrogen compounds of this series. |
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