Unexpected cyclization of 2-(2-aminophenyl)indoles with nitroalkenes to furnish indolo[3,2-: C] quinolines

Unexpected cyclization of 2-(2-aminophenyl)indoles with nitroalkenes to furnish indolo[3,2-: C] quinolines

The polyphosphoric acid-mediated reaction of 2-(2-aminophenyl)indenes with nitroalkenes was tested in the frame of synthetic studies towards CDK inhibitors with the paullone core. Unexpectedly, this reaction proceeded via a different mechanistic pathway affording derivatives of the natural alkaloid...

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Главные авторы:	Aksenov, A. V., Аксенов, А. В., Aksenov, D. A., Аксенов, Д. А., Griaznov, G. D., Грязнов, Г. Д., Aksenov, N. A., Аксенов, Н. А., Rubin, M. A., Рубин, М. А.
Формат:	Статья
Язык:	English
Опубликовано:	Royal Society of Chemistry 2018
Темы:	Positive ions CDK inhibitors Mechanistic pathways Mediated reactions Nitroalkenes Polyphosphoric acids Synthetic study Chemistry
Online-ссылка:	https://dspace.ncfu.ru:443/handle/20.500.12258/2446
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!

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