7-(2-Aryl-1-cyanovinyl)-1,2,3,4-tetrahydropyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles: Synthesis and Biological Activity

7-(2-Aryl-1-cyanovinyl)-1,2,3,4-tetrahydropyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles: Synthesis and Biological Activity

A new method was proposed for the preparation of 5-amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile by reaction of the potassium salt of malononitrile dimer with hydrazinium sulfate. The reaction of 5-amino-3(cyanomethyl)-1H-pyrazole-4-carbonitrile with aromatic aldehydes in the presence of catalyti...

पूर्ण विवरण

में बचाया:

ग्रंथसूची विवरण
मुख्य लेखकों:	Dotsenko, V. V., Доценко, В. В., Strelkov, V. D., Стрелков, В. Д., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
स्वरूप:	Статья
भाषा:	English
प्रकाशित:	2023
विषय:	5-amino-3-cyanomethyl-1H-pyrazole-4-carbonitrile Pyrazolo[1,5-a][1,3,5]triazines Mannich reaction Growth-promoting effect Antidote activity
ऑनलाइन पहुंच:	https://dspace.ncfu.ru/handle/20.500.12258/25522
टैग :	टैग जोड़ें कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन

New Heterocyclization Reactions with Malononitrile Dimer
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2024)

Reaction of ethoxymethylenemalonate with cyanothioacetamide in the presence of triethylamine: formation of 1,5-diamino-2,4-dicyano-5-thioxopenta-1,3-diene-1-thiolate and unexpected aminomethylation result
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2020)

New Heterocyclisation Reactions of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Some 1,3-Dielectrophilic Agents
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2022)

Some new reactions and properties of xanthane hydride (5-amino-1,2,4-dithiazole-3-thione)
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2018)

Reaction of 5-Amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with Hydroxycyclohexanones
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2019)

New methods of synthesis, structure and aminomethylation of 4-imino-2-(dicyanomethylene)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2021)

Synthesis and structure of new 3,7-diazabicyclo[3.3.1]nonane derivatives
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2018)

Synthesis and Structure of (2E)-3-Aryl(hetaryl)-2-[5-bromo-4-aryl(hetaryl)-1,3-thiazol-2-yl]acrylonitriles
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2021)

Mannich Reaction Involving 6-Amino-4-methyl-2-(thio)oxo-1,2-dihydropyridine-3,5-dicarbonitriles
द्वारा: Strelkov, V. D., और अन्य
प्रकाशित: (2023)

Synthesis and analgesic activity of new heterocyclic cyanothioacetamide derivatives
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2021)

Aminomethylation of Guareschi imides: synthesis of 2,4-dioxo-1H,5H-3,7-spiro[diazabicyclo[3.3.1]nonane-9,4'-piperidine]-1,5-dicarbonitriles
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2018)

1,6-Diamino-2-oxopyridine-3,5-dicarbonitrile Derivatives in the Mannich Reaction
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2021)

Reactions of beta-carbonyl-substituted 4H-chromenes and 1H-benzo[f]chromenes with 5-aminopyrazoles
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2021)

Reactions of β-Carbonyl-Substituted 4H-chromenes and 1H-benzo[f]Chromenes with 5-aminopyrazoles
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2021)

Introduction of tetrazol-1-yl and 5-methyltetrazol-1-yl substituents in the phenyl ring of dibenzo-18-crown-6
द्वारा: Aksenov, N. A., और अन्य
प्रकाशित: (2018)

7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2022)

[3 + 2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor
द्वारा: Aksenov, A. V., और अन्य
प्रकाशित: (2021)

Synthesis and properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2019)

Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2018)

Synthesis of 1,5-diazocin-2-ones
द्वारा: Aksenov, A. V., और अन्य
प्रकाशित: (2021)

2-Amino-4,5-dihydrothiophene-3-carbonitriles: A New Synthesis, Quantum Chemical Studies, and Mannich-Type Reactions Leading to New Hexahydrothieno[2,3-d]pyrimidines
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2021)

Synthesis and properties of new 4-oxo-4,5-dihydro-1,3-oxazolium perchlorates
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2019)

New Azepine-Furan Spirocyclic Structures in the Reaction of 4-Aroyl-1,2-dihydrobenzo[d]azepines and 2-Aroyl-4,5-dihydrophenanthreno[1,2-d]azepine with Formaldehyde
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2021)

Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes
द्वारा: Aksenov, D. A., और अन्य
प्रकाशित: (2020)

α-Amino acid-assisted autoxidation of naphthalene proton sponge affording 1,4-naphthoquinone nitrogen derivatives
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2023)

An access to 1H-cyclopenta[b]pyridine-4,5-diones via condensation of 6-nitro-1,2-o-quinone with arylamines and acetone
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2021)

A new Approach to the synthesis of functional derivatives of 3-(4-Pyridinyl)-1H-indole and 4-s(1H-Indol-3-yl)thieno[2,3-b]pyridine
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2018)

New Hybrid Molecules Based on Sulfur-Containing Nicotinonitriles: Synthesis, Analgesic Activity in Acetic Acid-Induced Writhing Test, and Molecular Docking Studies
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2022)

SNH-Arylamination of 1-methylquinolin-2(1H)-one Nitro Derivatives
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2021)

Synthesis and Aminomethylation of 2-Amino-4-(2-chlorophenyl)-6-(dicyanomethyl)-1,4-dihydropyridine-3,5-dicarbonitrile N-Methylmorpholinium Salt
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2022)

Crystal structure and properties of new benzimidazopyrido[2,3-b]indole-6-carbonitriles
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2024)

Oxidation of 4,6-Dimethyl-2-thioxo-1,2-dihydropyridine-3-carbonitriles with Potassium Ferricyanide: Synthesis and Molecular Docking of Bis(pyrid-2-yl) Disulfides
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2024)

Empirical determination of the degree of analgesic activity of some new 3-aminothieno[2,3-b]pyridines and 1,4-dihydropyridines based on a complex criterion
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2023)

Unexpected result of thiophosphorylation of 6-aminopyrano[2,3-c]pyrazole-5-carbonitrile derivative
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2019)

Nucleophilic dearomatization of 3-nitrobenzofurans by the action of 2-(1-arylethylidene)malononitriles
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2021)

Synthesis and In vivo Evaluation of Hepatoprotective Effects of Novel Sulfur-Containing 1,4-Dihydropyridines and 1,2,3,4-Tetrahydropyridines
द्वारा: Dotsenko, V. V., और अन्य
प्रकाशित: (2023)

Новые химические трансформации с использованием нитроолефинов
द्वारा: Александрова, Е. В.
प्रकाशित: (2023)

Preparation of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles via chemoselective сyclocondensation of electrophilically activated nitroalkanes to (thio)semicarbazides or thiohydrazides
द्वारा: Aksenov, N. A., और अन्य
प्रकाशित: (2020)

New β-[o-(5-oxopyrazol-3-yl)aryl]ethylamines and their unusual metastable betaine form
द्वारा: Demidov, O. P., और अन्य
प्रकाशित: (2023)

Synthesis of heterofunctional 1,3,7-triazapyrene derivatives by SNH and SNAr reactions
द्वारा: Borovlev, I. V., और अन्य
प्रकाशित: (2018)