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β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines

A cyclization–recyclization pathway for indirect 2-heteroarylation of tryptamines has been suggested by the example of introducing the pyrazolyl moiety. The process involves the intermediate cyclization of tryptamines into push–pull type β-carboline semi-products. The relative stability of the tauto...

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मुख्य लेखकों: Demidov, O. P., Демидов, О. П.
स्वरूप: Статья
भाषा:English
प्रकाशित: 2023
विषय:
ऑनलाइन पहुंच:https://dspace.ncfu.ru/handle/20.500.12258/25810
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id ir-20.500.12258-25810
record_format dspace
spelling ir-20.500.12258-258102023-11-16T13:27:40Z β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines Demidov, O. P. Демидов, О. П. 1-aroylmethylidene-1,2, 3, 4-tetrahydro-β-carbolines Tryptamines β-carbolines Recyclization Quantum chemical calculations Pyrazolylmelatonins 2-(pyrazol-3-yl)tryptamine 2-(pyrazol-3-yl)-O-methylserotonins A cyclization–recyclization pathway for indirect 2-heteroarylation of tryptamines has been suggested by the example of introducing the pyrazolyl moiety. The process involves the intermediate cyclization of tryptamines into push–pull type β-carboline semi-products. The relative stability of the tautomeric forms of 2-pyrazolyltryptamines has been estimated using the DFT method. 2023-11-16T13:26:32Z 2023-11-16T13:26:32Z 2023 Статья Zubenko, A.A., Divaeva, L.N., Morkovnik, A.S., Sochnev, V.S., Demidov, O.P., Chekrysheva, V.V., Klimenko, A.I., Svyatogorova, A.E. β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines // Mendeleev Communications. - 2023. - 33 (5). - pp. 645-647. - DOI: 10.1016/j.mencom.2023.09.018 http://hdl.handle.net/20.500.12258/25810 en Mendeleev Communications application/pdf application/pdf
institution СКФУ
collection Репозиторий
language English
topic 1-aroylmethylidene-1,2, 3, 4-tetrahydro-β-carbolines
Tryptamines
β-carbolines
Recyclization
Quantum chemical calculations
Pyrazolylmelatonins
2-(pyrazol-3-yl)tryptamine
2-(pyrazol-3-yl)-O-methylserotonins
spellingShingle 1-aroylmethylidene-1,2, 3, 4-tetrahydro-β-carbolines
Tryptamines
β-carbolines
Recyclization
Quantum chemical calculations
Pyrazolylmelatonins
2-(pyrazol-3-yl)tryptamine
2-(pyrazol-3-yl)-O-methylserotonins
Demidov, O. P.
Демидов, О. П.
β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
description A cyclization–recyclization pathway for indirect 2-heteroarylation of tryptamines has been suggested by the example of introducing the pyrazolyl moiety. The process involves the intermediate cyclization of tryptamines into push–pull type β-carboline semi-products. The relative stability of the tautomeric forms of 2-pyrazolyltryptamines has been estimated using the DFT method.
format Статья
author Demidov, O. P.
Демидов, О. П.
author_facet Demidov, O. P.
Демидов, О. П.
author_sort Demidov, O. P.
title β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
title_short β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
title_full β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
title_fullStr β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
title_full_unstemmed β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
title_sort β-carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
publishDate 2023
url https://dspace.ncfu.ru/handle/20.500.12258/25810
work_keys_str_mv AT demidovop bcarbolinesasintermediatesinindirectheteroarylationoftryptaminesexemplifiedbythesynthesisof2pyrazolyltryptamines
AT demidovop bcarbolinesasintermediatesinindirectheteroarylationoftryptaminesexemplifiedbythesynthesisof2pyrazolyltryptamines
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