β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines
A cyclization–recyclization pathway for indirect 2-heteroarylation of tryptamines has been suggested by the example of introducing the pyrazolyl moiety. The process involves the intermediate cyclization of tryptamines into push–pull type β-carboline semi-products. The relative stability of the tauto...
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2023
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ऑनलाइन पहुंच: | https://dspace.ncfu.ru/handle/20.500.12258/25810 |
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ir-20.500.12258-258102023-11-16T13:27:40Z β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines Demidov, O. P. Демидов, О. П. 1-aroylmethylidene-1,2, 3, 4-tetrahydro-β-carbolines Tryptamines β-carbolines Recyclization Quantum chemical calculations Pyrazolylmelatonins 2-(pyrazol-3-yl)tryptamine 2-(pyrazol-3-yl)-O-methylserotonins A cyclization–recyclization pathway for indirect 2-heteroarylation of tryptamines has been suggested by the example of introducing the pyrazolyl moiety. The process involves the intermediate cyclization of tryptamines into push–pull type β-carboline semi-products. The relative stability of the tautomeric forms of 2-pyrazolyltryptamines has been estimated using the DFT method. 2023-11-16T13:26:32Z 2023-11-16T13:26:32Z 2023 Статья Zubenko, A.A., Divaeva, L.N., Morkovnik, A.S., Sochnev, V.S., Demidov, O.P., Chekrysheva, V.V., Klimenko, A.I., Svyatogorova, A.E. β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines // Mendeleev Communications. - 2023. - 33 (5). - pp. 645-647. - DOI: 10.1016/j.mencom.2023.09.018 http://hdl.handle.net/20.500.12258/25810 en Mendeleev Communications application/pdf application/pdf |
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СКФУ |
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Репозиторий |
language |
English |
topic |
1-aroylmethylidene-1,2, 3, 4-tetrahydro-β-carbolines Tryptamines β-carbolines Recyclization Quantum chemical calculations Pyrazolylmelatonins 2-(pyrazol-3-yl)tryptamine 2-(pyrazol-3-yl)-O-methylserotonins |
spellingShingle |
1-aroylmethylidene-1,2, 3, 4-tetrahydro-β-carbolines Tryptamines β-carbolines Recyclization Quantum chemical calculations Pyrazolylmelatonins 2-(pyrazol-3-yl)tryptamine 2-(pyrazol-3-yl)-O-methylserotonins Demidov, O. P. Демидов, О. П. β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines |
description |
A cyclization–recyclization pathway for indirect 2-heteroarylation of tryptamines has been suggested by the example of introducing the pyrazolyl moiety. The process involves the intermediate cyclization of tryptamines into push–pull type β-carboline semi-products. The relative stability of the tautomeric forms of 2-pyrazolyltryptamines has been estimated using the DFT method. |
format |
Статья |
author |
Demidov, O. P. Демидов, О. П. |
author_facet |
Demidov, O. P. Демидов, О. П. |
author_sort |
Demidov, O. P. |
title |
β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines |
title_short |
β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines |
title_full |
β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines |
title_fullStr |
β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines |
title_full_unstemmed |
β-Carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines |
title_sort |
β-carbolines as intermediates in indirect heteroarylation of tryptamines exemplified by the synthesis of 2-pyrazolyltryptamines |
publishDate |
2023 |
url |
https://dspace.ncfu.ru/handle/20.500.12258/25810 |
work_keys_str_mv |
AT demidovop bcarbolinesasintermediatesinindirectheteroarylationoftryptaminesexemplifiedbythesynthesisof2pyrazolyltryptamines AT demidovop bcarbolinesasintermediatesinindirectheteroarylationoftryptaminesexemplifiedbythesynthesisof2pyrazolyltryptamines |
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1809808971289067520 |