Synthesis and Stability Study of Iron(II) Ascorbatolizinate

Within the framework of this work, the synthesis and study of the stability of a triple chelate iron-containing complex, iron (II) ascorbatolizinate, was carried out. For the synthesis of iron (II) ascorbatolizinate, lysine monohydrochloride, ascorbic acid, iron sulfate, and barium hydroxide were us...

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Main Authors:	Blinov, A. V., Блинов, А. В., Gvozdenko, A. A., Гвозденко, А. А., Golik, A. B., Голик, А. Б.
Format:	Статья
Language:	English
Published:	2024
Subjects:	Functional foods Quantum chemical modeling Stability Iron deficiency anemia Iron (II) ascorbatolizinate
Online Access:	https://dspace.ncfu.ru/handle/20.500.12258/26463
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id	ir-20.500.12258-26463
record_format	dspace
spelling	ir-20.500.12258-264632024-02-15T08:20:52Z Synthesis and Stability Study of Iron(II) Ascorbatolizinate Blinov, A. V. Блинов, А. В. Gvozdenko, A. A. Гвозденко, А. А. Golik, A. B. Голик, А. Б. Functional foods Quantum chemical modeling Stability Iron deficiency anemia Iron (II) ascorbatolizinate Within the framework of this work, the synthesis and study of the stability of a triple chelate iron-containing complex, iron (II) ascorbatolizinate, was carried out. For the synthesis of iron (II) ascorbatolizinate, lysine monohydrochloride, ascorbic acid, iron sulfate, and barium hydroxide were used. To study the stability of iron (II) ascorbatolizinate, a multifactorial experiment was carried out, which included three input parameters and three levels of variation. The active acidity of the medium, the mixing time, and the temperature of the solution were considered as input parameters. The output parameters were changes in the value of optical density and a change in the value of the redox potential. Within the framework of the study, the optimal configuration of iron (II) ascorbatolizinate was determined by the method of quantum chemical modeling. It has been established that the configuration in which the interaction occurs through the carboxyl group and α-amino group of lysine and through the C2 and C3 hydroxyl groups of ascorbic acid is optimal. It has been shown that iron (II) ascorbatolizinate is chemically stable at the following technological parameters: pH from 4 to 9, exposure time from 5 to 20 min, and temperature from 25 to 60 °C. 2024-02-15T08:19:58Z 2024-02-15T08:19:58Z 2023 Статья Blinov, A., Gvozdenko, A., Golik, A., Maslova, A., Verevkina, M. Synthesis and Stability Study of Iron(II) Ascorbatolizinate // AIP Conference Proceedings. - 2023. - 2931 (1). - статья № 060004. - DOI: 10.1063/5.0178814 http://hdl.handle.net/20.500.12258/26463 en AIP Conference Proceedings application/pdf
institution	СКФУ
collection	Репозиторий
language	English
topic	Functional foods Quantum chemical modeling Stability Iron deficiency anemia Iron (II) ascorbatolizinate
spellingShingle	Functional foods Quantum chemical modeling Stability Iron deficiency anemia Iron (II) ascorbatolizinate Blinov, A. V. Блинов, А. В. Gvozdenko, A. A. Гвозденко, А. А. Golik, A. B. Голик, А. Б. Synthesis and Stability Study of Iron(II) Ascorbatolizinate
description	Within the framework of this work, the synthesis and study of the stability of a triple chelate iron-containing complex, iron (II) ascorbatolizinate, was carried out. For the synthesis of iron (II) ascorbatolizinate, lysine monohydrochloride, ascorbic acid, iron sulfate, and barium hydroxide were used. To study the stability of iron (II) ascorbatolizinate, a multifactorial experiment was carried out, which included three input parameters and three levels of variation. The active acidity of the medium, the mixing time, and the temperature of the solution were considered as input parameters. The output parameters were changes in the value of optical density and a change in the value of the redox potential. Within the framework of the study, the optimal configuration of iron (II) ascorbatolizinate was determined by the method of quantum chemical modeling. It has been established that the configuration in which the interaction occurs through the carboxyl group and α-amino group of lysine and through the C2 and C3 hydroxyl groups of ascorbic acid is optimal. It has been shown that iron (II) ascorbatolizinate is chemically stable at the following technological parameters: pH from 4 to 9, exposure time from 5 to 20 min, and temperature from 25 to 60 °C.
format	Статья
author	Blinov, A. V. Блинов, А. В. Gvozdenko, A. A. Гвозденко, А. А. Golik, A. B. Голик, А. Б.
author_facet	Blinov, A. V. Блинов, А. В. Gvozdenko, A. A. Гвозденко, А. А. Golik, A. B. Голик, А. Б.
author_sort	Blinov, A. V.
title	Synthesis and Stability Study of Iron(II) Ascorbatolizinate
title_short	Synthesis and Stability Study of Iron(II) Ascorbatolizinate
title_full	Synthesis and Stability Study of Iron(II) Ascorbatolizinate
title_fullStr	Synthesis and Stability Study of Iron(II) Ascorbatolizinate
title_full_unstemmed	Synthesis and Stability Study of Iron(II) Ascorbatolizinate
title_sort	synthesis and stability study of iron(ii) ascorbatolizinate
publishDate	2024
url	https://dspace.ncfu.ru/handle/20.500.12258/26463
work_keys_str_mv	AT blinovav synthesisandstabilitystudyofironiiascorbatolizinate AT blinovav synthesisandstabilitystudyofironiiascorbatolizinate AT gvozdenkoaa synthesisandstabilitystudyofironiiascorbatolizinate AT gvozdenkoaa synthesisandstabilitystudyofironiiascorbatolizinate AT golikab synthesisandstabilitystudyofironiiascorbatolizinate AT golikab synthesisandstabilitystudyofironiiascorbatolizinate
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Synthesis and Stability Study of Iron(II) Ascorbatolizinate

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