One-step synthesis of 4-methyl-2-substituted quinazoline-3-oxides via polyphosphoric acid catalyzed acylation of electron-rich anilides with nitroethane
A diverse set of 4-methyl-2-substituted quinazoline-3-oxides has been prepared using polyphosphoric acid both as a reaction medium and a Brønsted-acid catalyst. The reaction proceeds in a domino fashion via the formation of a corresponding oxime followed by exo-trig cyclization and elimination of a...
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| Main Authors: | , , , , , , , , , |
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| Format: | Статья |
| Language: | English |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://dspace.ncfu.ru/handle/20.500.12258/26766 |
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