Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM

The conducted research is devoted to investigation of a condition of mast cells system of thymus, liver and adrenal glands of mammals at an acute experimental inflammation under the influence of an immuno-modulatory preparation "NICA-EM". It is shown that at the studied model of an inflamm...

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मुख्य लेखकों:	Timchenko, L. D., Тимченко, Л. Д., Rzhepakovsky, I. V., Ржепаковский, И. В., Blazhnova, G. N., Блажнова, Г. Н., Bondareva, N. I., Бондарева, Н. И.
स्वरूप:	Статья
भाषा:	English
प्रकाशित:	Research Journal of Pharmaceutical, Biological and Chemical Sciences 2018
विषय:	Adrenal gland Immunomodulation Inflammation Liver Mast cells Thymus
ऑनलाइन पहुंच:	https://www.scopus.com/record/display.uri?eid=2-s2.0-84962499221&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=ea54bb63d2e1600c13ab4f3297a2ca8e&sot=afnl&sdt=sisr&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Mast+cells+of+thymus%2c+adrenal+glands+and+liver+at+the+acute+experimental+inflammation+and+its+correction+by+preparation+NICA-EM%29&relpos=0&citeCnt=0&searchTerm= https://dspace.ncfu.ru/handle/20.500.12258/3416
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record_format	dspace
spelling	ir-20.500.12258-34162020-07-31T11:36:54Z Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM Timchenko, L. D. Тимченко, Л. Д. Rzhepakovsky, I. V. Ржепаковский, И. В. Blazhnova, G. N. Блажнова, Г. Н. Bondareva, N. I. Бондарева, Н. И. Adrenal gland Immunomodulation Inflammation Liver Mast cells Thymus The conducted research is devoted to investigation of a condition of mast cells system of thymus, liver and adrenal glands of mammals at an acute experimental inflammation under the influence of an immuno-modulatory preparation "NICA-EM". It is shown that at the studied model of an inflammation in control group there is a decrease in number of MCs in a thymus and increase in a liver and adrenal glands. Thus the number of the degranulated MCs increases in all studied organs. Preparation "NICA-EM" renders an anti-inflammatory effect, and system of mast cells of an organism of rats treated with the preparation reacts in the universal way. Thus, action of a preparation brings to uncertainly significant decrease in number of MCs in a thymus and liver in comparison with parameters of intact animals, against increase in their number in adrenal glands. The num-ber of the degranulated MCs in comparison with intact animals increases in thymus and adrenal glands, but thus their number is less, than in control. Thus, the conducted research testifies that application of a prepara-tion "NICA-EM" leads to intensification of degranulation of MCs in the studied organs at acute inflammatory reaction against less considerable, than in control, migration of MCs from a thymus 2018-11-14T14:14:17Z 2018-11-14T14:14:17Z 2016 Статья Areshidze, D.A., Timchenko, L.D., Rzhepakovsky, I.V., Kozlova, M.A., Syomin, I.A., Blazhnova, G.N., Bondareva, N.I. Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM // Research Journal of Pharmaceutical, Biological and Chemical Sciences. - 2016. - Volume 7. - Issue 2. - Pages 1620-1629 https://www.scopus.com/record/display.uri?eid=2-s2.0-84962499221&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=ea54bb63d2e1600c13ab4f3297a2ca8e&sot=afnl&sdt=sisr&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Mast+cells+of+thymus%2c+adrenal+glands+and+liver+at+the+acute+experimental+inflammation+and+its+correction+by+preparation+NICA-EM%29&relpos=0&citeCnt=0&searchTerm= http://hdl.handle.net/20.500.12258/3416 en Research Journal of Pharmaceutical, Biological and Chemical Sciences application/pdf application/pdf Research Journal of Pharmaceutical, Biological and Chemical Sciences
institution	СКФУ
collection	Репозиторий
language	English
topic	Adrenal gland Immunomodulation Inflammation Liver Mast cells Thymus
spellingShingle	Adrenal gland Immunomodulation Inflammation Liver Mast cells Thymus Timchenko, L. D. Тимченко, Л. Д. Rzhepakovsky, I. V. Ржепаковский, И. В. Blazhnova, G. N. Блажнова, Г. Н. Bondareva, N. I. Бондарева, Н. И. Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM
description	The conducted research is devoted to investigation of a condition of mast cells system of thymus, liver and adrenal glands of mammals at an acute experimental inflammation under the influence of an immuno-modulatory preparation "NICA-EM". It is shown that at the studied model of an inflammation in control group there is a decrease in number of MCs in a thymus and increase in a liver and adrenal glands. Thus the number of the degranulated MCs increases in all studied organs. Preparation "NICA-EM" renders an anti-inflammatory effect, and system of mast cells of an organism of rats treated with the preparation reacts in the universal way. Thus, action of a preparation brings to uncertainly significant decrease in number of MCs in a thymus and liver in comparison with parameters of intact animals, against increase in their number in adrenal glands. The num-ber of the degranulated MCs in comparison with intact animals increases in thymus and adrenal glands, but thus their number is less, than in control. Thus, the conducted research testifies that application of a prepara-tion "NICA-EM" leads to intensification of degranulation of MCs in the studied organs at acute inflammatory reaction against less considerable, than in control, migration of MCs from a thymus
format	Статья
author	Timchenko, L. D. Тимченко, Л. Д. Rzhepakovsky, I. V. Ржепаковский, И. В. Blazhnova, G. N. Блажнова, Г. Н. Bondareva, N. I. Бондарева, Н. И.
author_facet	Timchenko, L. D. Тимченко, Л. Д. Rzhepakovsky, I. V. Ржепаковский, И. В. Blazhnova, G. N. Блажнова, Г. Н. Bondareva, N. I. Бондарева, Н. И.
author_sort	Timchenko, L. D.
title	Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM
title_short	Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM
title_full	Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM
title_fullStr	Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM
title_full_unstemmed	Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM
title_sort	mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation nica-em
publisher	Research Journal of Pharmaceutical, Biological and Chemical Sciences
publishDate	2018
url	https://www.scopus.com/record/display.uri?eid=2-s2.0-84962499221&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=ea54bb63d2e1600c13ab4f3297a2ca8e&sot=afnl&sdt=sisr&cluster=scopubyr%2c%222016%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Mast+cells+of+thymus%2c+adrenal+glands+and+liver+at+the+acute+experimental+inflammation+and+its+correction+by+preparation+NICA-EM%29&relpos=0&citeCnt=0&searchTerm= https://dspace.ncfu.ru/handle/20.500.12258/3416
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Mast cells of thymus, adrenal glands and liver at the acute experimental inflammation and its correction by preparation NICA-EM

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