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A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities

A nitroalkane-based approach to one-pot three-component synthesis of isocryptolepine and its analogs with potent anti-cancer activities

A second generation polyphosphoric acid-mediated one-pot three-component synthesis of indoloquinoline scaffold is developed. This improved version of the process involves electrophilically activated nitroalkanes for the installation of strategic C-C and C-N bonds and ring C assembly. This modificati...

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Главные авторы: Aksenov, N. A., Аксенов, Н. А., Aksenov, A. V., Аксенов, А. В., Aksenov, D. A., Аксенов, Д. А., Ovcharov, S. N., Овчаров, С. Н., Rubin, M. A., Рубин, М. А.
格式: Статья
语言:English
出版: ROYAL SOC CHEMISTRY 2018
主题:
Anticancer activity
Change operations
Concise synthesis
Polyphosphoric acids
Second generation
Synthetic analogs
Synthetic application
Three component
在线阅读:https://www.scopus.com/record/display.uri?eid=2-s2.0-85056392927&origin=resultslist&sort=plf-f&src=s&st1=A+nitroalkane-based+approach+to+one-pot+three-component+synthesis+of+isocryptolepine+and+its+analogs+with+potent+anti-cancer+activities&st2=&sid=24b550a4004eff540c1f66bf75dbf431&sot=b&sdt=b&sl=150&s=TITLE-ABS-KEY%28A+nitroalkane-based+approach+to+one-pot+three-component+synthesis+of+isocryptolepine+and+its+analogs+with+potent+anti-cancer+activities%29&relpos=0&citeCnt=0&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/3475
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https://www.scopus.com/record/display.uri?eid=2-s2.0-85056392927&origin=resultslist&sort=plf-f&src=s&st1=A+nitroalkane-based+approach+to+one-pot+three-component+synthesis+of+isocryptolepine+and+its+analogs+with+potent+anti-cancer+activities&st2=&sid=24b550a4004eff540c1f66bf75dbf431&sot=b&sdt=b&sl=150&s=TITLE-ABS-KEY%28A+nitroalkane-based+approach+to+one-pot+three-component+synthesis+of+isocryptolepine+and+its+analogs+with+potent+anti-cancer+activities%29&relpos=0&citeCnt=0&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/3475

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