Synthesis of heterofunctional 1,3,7-triazapyrene derivatives by SNH and SNAr reactions
1,3,7-Triazapyrene reacts with amino alcohols in aqueous medium in the presence of K3Fe(CN)6 or in the system DMSO-KOH-O2 via oxidative nucleophilic substitution of hydrogen to give the corresponding 6-hydroxyalkylamino derivatives. The reaction of 1,3,7-triazapyrene with sodium amide in DMSO at roo...
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