One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes

A one-pot synthesis of various GABA amides has been demostrated, employing the nucleophilic addition of primary and secondary amines across the double bond of cyclopropene-3-carboxamides, followed by ring-opening of the resulting donor-acceptor cyclopropanes and subsequent in situ reduction of enami...

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Главные авторы:	Rubin, M. A., Рубин, М. А.
Formato:	Статья
Idioma:	English
Publicado:	Royal Society of Chemistry 2018
Темы:	Addition reaction Amides Amines One-pot synthesis
Acceso en liña:	https://www.scopus.com/record/display.uri?eid=2-s2.0-84939615101&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=7bd8844b21db9e8d960886763fe328ab&sot=afnl&sdt=cl&cluster=scopubyr%2c%222015%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=22&citeCnt=9&searchTerm= https://dspace.ncfu.ru/handle/20.500.12258/3708
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spelling	ir-20.500.12258-37082020-09-14T14:28:53Z One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes Rubin, M. A. Рубин, М. А. Addition reaction Amides Amines One-pot synthesis A one-pot synthesis of various GABA amides has been demostrated, employing the nucleophilic addition of primary and secondary amines across the double bond of cyclopropene-3-carboxamides, followed by ring-opening of the resulting donor-acceptor cyclopropanes and subsequent in situ reduction of enamine (imine) intermediates 2018-12-18T12:33:04Z 2018-12-18T12:33:04Z 2015 Статья Maslivetc, V.A., Rubina, M., Rubin, M. One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes // Organic and Biomolecular Chemistry. - 2015. - Volume 13. - Issue 34. - Pages 8993-8995 https://www.scopus.com/record/display.uri?eid=2-s2.0-84939615101&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=7bd8844b21db9e8d960886763fe328ab&sot=afnl&sdt=cl&cluster=scopubyr%2c%222015%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=22&citeCnt=9&searchTerm= http://hdl.handle.net/20.500.12258/3708 en Organic and Biomolecular Chemistry application/pdf application/pdf Royal Society of Chemistry
institution	СКФУ
collection	Репозиторий
language	English
topic	Addition reaction Amides Amines One-pot synthesis
spellingShingle	Addition reaction Amides Amines One-pot synthesis Rubin, M. A. Рубин, М. А. One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes
description	A one-pot synthesis of various GABA amides has been demostrated, employing the nucleophilic addition of primary and secondary amines across the double bond of cyclopropene-3-carboxamides, followed by ring-opening of the resulting donor-acceptor cyclopropanes and subsequent in situ reduction of enamine (imine) intermediates
format	Статья
author	Rubin, M. A. Рубин, М. А.
author_facet	Rubin, M. A. Рубин, М. А.
author_sort	Rubin, M. A.
title	One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes
title_short	One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes
title_full	One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes
title_fullStr	One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes
title_full_unstemmed	One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes
title_sort	one-pot synthesis of gaba amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes
publisher	Royal Society of Chemistry
publishDate	2018
url	https://www.scopus.com/record/display.uri?eid=2-s2.0-84939615101&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=7bd8844b21db9e8d960886763fe328ab&sot=afnl&sdt=cl&cluster=scopubyr%2c%222015%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&relpos=22&citeCnt=9&searchTerm= https://dspace.ncfu.ru/handle/20.500.12258/3708
work_keys_str_mv	AT rubinma onepotsynthesisofgabaamidesviathenucleophilicadditionofaminesto33disubstitutedcyclopropenes AT rubinma onepotsynthesisofgabaamidesviathenucleophilicadditionofaminesto33disubstitutedcyclopropenes
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One-pot synthesis of GABA amides via the nucleophilic addition of amines to 3,3-disubstituted cyclopropenes

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