Activity of 2-aryl-2-(3-indolyl)acetohydroxamates against drug-resistant cancer cells

Activity of 2-aryl-2-(3-indolyl)acetohydroxamates against drug-resistant cancer cells

Many types of tumor, including glioma, melanoma, non-small cell lung, esophageal, and head and neck cancer, among others, are intrinsically resistant to apoptosis induction and poorly responsive to current therapies with proapoptotic agents. In addition, tumors often develop multidrug resistance bas...

Полное описание

Сохранить в:

Библиографические подробности
Главные авторы:	Aksenov, A. V., Аксенов, А. В., Smirnov, A. N., Смирнов, А. Н., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Формат:	Статья
Язык:	English
Опубликовано:	American Chemical Society 2018
Темы:	2 aryl 2 (3 indolyl)acetohydroxamate derivative Acetohydroxamic acid Antineoplastic agent Unclassified drug Hydroxamic acid Indole derivative
Online-ссылка:	https://dspace.ncfu.ru/handle/20.500.12258/3725
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!

Схожие документы

Methylation of 2-Aryl-2-(3-indolyl)acetohydroxamic acids and evaluation of cytotoxic activity of the products
Автор: Aksenov, D. A., и др.
Опубликовано: (2022)

A new series of acetohydroxamates shows in vitro and in vivo anticancer activity against melanoma
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)

An efficient synthesis of (3-indolyl)acetonitriles by reduction of hydroxamic acids
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

First synthesis of heterocyclic allenes-benzazecine derivatives
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Synthesis and luminescent properties of Eu3+, Gd3+, and Tb3+ complexes with quinoline-4-carboxylic acids
Автор: Aksenova, I. V., и др.
Опубликовано: (2020)

Synthesis and some properties of new 5-Hydroxy-2-[(hetarylthio)methyl]-4H-pyran-4-ones
Автор: Dotsenko, V. V., и др.
Опубликовано: (2021)

Oxidative coupling of tetraalkynyltin with aldehydes leading to alkynyl ketones
Автор: Aksenov, N. A., и др.
Опубликовано: (2018)

Rational design of an efficient one-pot synthesis of 6H-pyrrolo[2,3,4- gh] perimidines in polyphosphoric acid
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Synthesis and characterization of selenium nanoparticles stabilized with oxyethylated alkylphenol (neonol) for potential modification of fabric materials
Автор: Rekhman, Z. A., и др.
Опубликовано: (2024)

Numerical method for fractional sub-diffusion equation with space–time varying diffusivity and smooth solution
Автор: Alikhanov, A. A., и др.
Опубликовано: (2025)

Synthesis and Regiospecific Bromination of (2E,4E)-5-Aryl-2-(4-arylthiazol-2-yl)penta-2,4-dienenitrile
Автор: Dotsenko, V. V., и др.
Опубликовано: (2021)

Synthesis and characterization of biopolymer-based copper carbonate nanoparticles
Автор: Blinov, A. V., и др.
Опубликовано: (2025)

γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles
Автор: Aksenov, N. A., и др.
Опубликовано: (2024)

[3 + 2]-Annulation of pyridinium ylides with 1-chloro-2-nitrostyrenes unveils a tubulin polymerization inhibitor
Автор: Aksenov, A. V., и др.
Опубликовано: (2021)

Acid-Base and Photocatalytic Properties of the CeO2-Ag Nanocomposites
Автор: Kravtsov, A. A., и др.
Опубликовано: (2023)

Synthesis of New (2E,4E)-2-Cyano-5-phenylpenta-2,4-dienethioamide Derivatives
Автор: Aksenov, N. A., и др.
Опубликовано: (2025)

A Diastereoselective Assembly of Tetralone Derivatives via a Tandem Michael Reaction and ipso-Substitution of the Nitro Group
Автор: Aksenov, N. A., и др.
Опубликовано: (2023)

Preparation of spiro[indole-3,5′-isoxazoles] via Grignard conjugate addition/spirocyclization sequence
Автор: Aksenov, A. V., и др.
Опубликовано: (2021)

Synthesis and luminescent properties of Eu3+ and Tb3+ Complexes with Coumarin-3-carboxylic Acids
Автор: Dotsenko, V. V., и др.
Опубликовано: (2021)

Determination of 2,4-Dichlorophenoxyacetic Acid and Its Metabolite in Soils by Gas Chromatography–Mass Spectrometry after Preconcentration Using Magnetic Charcoal Based on Rice Husk
Автор: Sypko, K. S., и др.
Опубликовано: (2025)

Synthesis of (2E,4E)-2-(4-Aryl-1,3-selenazol-2-yl)-5-phenylpenta-2,4-dienenitriles
Автор: Aksenov, N. A., и др.
Опубликовано: (2025)

A high-order compact difference scheme for the multi-term time-fractional Sobolev-type convection-diffusion equation
Автор: Alikhanov, A. A., и др.
Опубликовано: (2025)

Synthesis, Structure, and Bromination of 3-(Arylamino)-2-(4-arylthiazol-2-yl)acrylonitriles
Автор: Dotsenko, V. V., и др.
Опубликовано: (2025)

Synthesis of isothio- and isoselenocyanates of adamantane series and their cytotoxic activity
Автор: Aksenov, D. A., и др.
Опубликовано: (2025)

Mn-mediated sequential three-component domino Knoevenagel/cyclization/Michael addition/oxidative cyclization reaction towards annulated imidazo[1,2-a]pyridines
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)

Betti reaction of 2-naphthol, furfural, and acetamide: an unexpected case of secondary carbo-Piancatelli rearrangement
Автор: Demidov, O. P., и др.
Опубликовано: (2019)

Synthesis and luminescent properties of Eu3+, Gd3+, and Tb3+ complex compounds with some N-substituted phthalamic acids
Автор: Dotsenko, V. V., и др.
Опубликовано: (2021)

5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Electrophilically activated nitroalkanes in the synthesis of substituted 1,3,4-oxadiazoles from amino acid derivatives
Автор: Aksenov, A. V., и др.
Опубликовано: (2022)

Organic chemistry. History and mutual relations of universities of Russia
Автор: Aksenov, A. V., и др.
Опубликовано: (2018)

Reaction of tetra(phenylethynyl)tin with aromatic aldehydes: a new one-pot method for the synthesis of α-acetylene ketones
Автор: Dotsenko, V. V., и др.
Опубликовано: (2020)

The Reactions of N,N′-Diphenyldithiomalondiamide with Arylmethylidene Meldrum’s Acids
Автор: Dotsenko, V. V., и др.
Опубликовано: (2023)

Dibenzoylmethane in the Synthesis of Selenium Di- and Tetrahydropyridine-3-carbonitriles
Автор: Aksenov, N. A., и др.
Опубликовано: (2025)

Improved method for preparation of 3-(1H-Indol-3-yl)benzofuran-2(3H)-ones
Автор: Grishin, I. Y., и др.
Опубликовано: (2022)

Direct C-H functionalization of arenes in reactions with nitroalkanes and nitroalkenes in polyphosphoric acids
Автор: Aksenov, A. V., и др.
Опубликовано: (2019)

One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-Ylidene)-2-Arylacetonitriles
Автор: Aksenov, N. A., и др.
Опубликовано: (2022)

Synthesis of 3,4-dihydroisoquinolines using nitroalkanes in polyphosphoric acid
Автор: Aksenov, N. A., и др.
Опубликовано: (2019)

One-Pot Synthesis of N-Fused Quinolone-4 Tetracyclic Scaffolds from 2,2-Disubstituted Indolin-3-ones
Автор: Arutiunov, N. A., и др.
Опубликовано: (2024)

Synthesis of 2,2-Dimethyl-2,3-dihydropyrido[3′,2′:4,5]-thieno[3,2-d]pyrimidin-4(1H)-ones by Reaction of 3-Aminothieno[2,3-b]pyridine-2-carboxamides with Acetone
Автор: Dotsenko, V. V., и др.
Опубликовано: (2025)

Synthesis and Aminomethylation of 6-Amino-2-(dicyanomethylene)-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile Morpholinium Salt
Автор: Dotsenko, V. V., и др.
Опубликовано: (2021)