Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome
In this investigation, we revealed that application of the biostimulating tissue preparation based on chicken embryos ("STEMB") at experimental hepatorenal syndrome showed improvement of the morphofunctional parameters of a liver. Under the influence of a biostimulator the relative mass of...
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Lifescience Global
2019
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ir-20.500.12258-42482020-09-11T14:37:12Z Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome Timchenko, L. D. Тимченко, Л. Д. Rzhepakovsky, I. V. Ржепаковский, И. В. Piskov, S. I. Писков, С. И. Vakulin, V. N. Вакулин, В. Н. Biogenic stimulants Chicken embryo Hepatorenal syndrome Kidney Liver Tissue therapy In this investigation, we revealed that application of the biostimulating tissue preparation based on chicken embryos ("STEMB") at experimental hepatorenal syndrome showed improvement of the morphofunctional parameters of a liver. Under the influence of a biostimulator the relative mass of a liver considerably decreased and biochemical markers of a condition of a liver (total bilirubin, ALT, AST) returned to normal. Besides, under the influence of "STEMB" the tendency to normalization of mitotic, apoptotic and binuclear cells index of liver tissues and considerable decrease in a necrotic index is observed. Results of the research conducted by us allow to make a conclusion on possibility of inclusion of "STEMB" in a complex therapy of HRS for treatment of the injuries of a liver which are its main reason 2019-02-11T13:03:54Z 2019-02-11T13:03:54Z 2015 Статья Areshidze, D.A., Timchenko, L.D., Kozlova, M.A., Syomin, I.A., Rzhepakovsky, I.V., Piskov, S.I., Vakulin, V.N. Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome // Journal of Pharmacy and Nutrition Sciences. - 2015. - Volume 5. - Issue 3. - Pages 186-193 https://www.scopus.com/record/display.uri?eid=2-s2.0-84940531359&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=de977e17ed6d4c180dedf3309644dde7&sot=afnl&sdt=sisr&cluster=scopubyr%2c%222015%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Influence+of+biologically+active+substance+%22STEMB%22+on+a+morphofunctional+condition+of+a+liver+and+kidneys+of+rats+at+an+experimental+hepatorenal+syndrome%29&relpos=0&citeCnt=1&searchTerm= http://hdl.handle.net/20.500.12258/4248 en Journal of Pharmacy and Nutrition Sciences application/pdf Lifescience Global |
| institution |
СКФУ |
| collection |
Репозиторий |
| language |
English |
| topic |
Biogenic stimulants Chicken embryo Hepatorenal syndrome Kidney Liver Tissue therapy |
| spellingShingle |
Biogenic stimulants Chicken embryo Hepatorenal syndrome Kidney Liver Tissue therapy Timchenko, L. D. Тимченко, Л. Д. Rzhepakovsky, I. V. Ржепаковский, И. В. Piskov, S. I. Писков, С. И. Vakulin, V. N. Вакулин, В. Н. Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome |
| description |
In this investigation, we revealed that application of the biostimulating tissue preparation based on chicken embryos ("STEMB") at experimental hepatorenal syndrome showed improvement of the morphofunctional parameters of a liver. Under the influence of a biostimulator the relative mass of a liver considerably decreased and biochemical markers of a condition of a liver (total bilirubin, ALT, AST) returned to normal. Besides, under the influence of "STEMB" the tendency to normalization of mitotic, apoptotic and binuclear cells index of liver tissues and considerable decrease in a necrotic index is observed. Results of the research conducted by us allow to make a conclusion on possibility of inclusion of "STEMB" in a complex therapy of HRS for treatment of the injuries of a liver which are its main reason |
| format |
Статья |
| author |
Timchenko, L. D. Тимченко, Л. Д. Rzhepakovsky, I. V. Ржепаковский, И. В. Piskov, S. I. Писков, С. И. Vakulin, V. N. Вакулин, В. Н. |
| author_facet |
Timchenko, L. D. Тимченко, Л. Д. Rzhepakovsky, I. V. Ржепаковский, И. В. Piskov, S. I. Писков, С. И. Vakulin, V. N. Вакулин, В. Н. |
| author_sort |
Timchenko, L. D. |
| title |
Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome |
| title_short |
Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome |
| title_full |
Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome |
| title_fullStr |
Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome |
| title_full_unstemmed |
Influence of biologically active substance "STEMB" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome |
| title_sort |
influence of biologically active substance "stemb" on a morphofunctional condition of a liver and kidneys of rats at an experimental hepatorenal syndrome |
| publisher |
Lifescience Global |
| publishDate |
2019 |
| url |
https://www.scopus.com/record/display.uri?eid=2-s2.0-84940531359&origin=resultslist&sort=plf-f&src=s&nlo=1&nlr=20&nls=afprfnm-t&affilName=north+caucasus+federal+university&sid=de977e17ed6d4c180dedf3309644dde7&sot=afnl&sdt=sisr&cluster=scopubyr%2c%222015%22%2ct&sl=53&s=%28AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29%29&ref=%28Influence+of+biologically+active+substance+%22STEMB%22+on+a+morphofunctional+condition+of+a+liver+and+kidneys+of+rats+at+an+experimental+hepatorenal+syndrome%29&relpos=0&citeCnt=1&searchTerm= https://dspace.ncfu.ru/handle/20.500.12258/4248 |
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