Changes of hemostasis indicators in women in accuracy practice

Objectives: To study changes in the parameters of thromboelastometry and the plasma link of the hemostasis system in women with uncomplicated pregnancy and with manifestations of thrombophilia in the perinatal period. Methods: The analysis of indices of thromboelastometry and coagulogram in 408...

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Egile Nagusiak:	Muratova, A. Y., Муратова, А. Ю., Denisova, E. V., Денисова, Е. В., Melchenko, E. A., Мельченко, Е. А., Glizhova, T. N., Глижова, Т. Н., Andrusenko, S. F., Андрусенко, С. Ф., Suprunchuk, V. E., Супрунчук, В. Е.
Formatua:	Статья
Hizkuntza:	English
Argitaratua:	ENTOMOLOGY & APPLIED SCIENCE RESEARCH LETTERS-EASLETTERS 2018
Gaiak:	Pregnant Women Thrombophilia Thromboelastometry Hypercoagulation Plasma Haemostasis
Sarrera elektronikoa:	http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=1&SID=D4CqLgJyMUbdkXB1tTT&page=1&doc=27 https://dspace.ncfu.ru:443/handle/20.500.12258/492
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spelling	ir-20.500.12258-4922020-09-07T12:23:20Z Changes of hemostasis indicators in women in accuracy practice Muratova, A. Y. Муратова, А. Ю. Denisova, E. V. Денисова, Е. В. Melchenko, E. A. Мельченко, Е. А. Glizhova, T. N. Глижова, Т. Н. Andrusenko, S. F. Андрусенко, С. Ф. Suprunchuk, V. E. Супрунчук, В. Е. Pregnant Women Thrombophilia Thromboelastometry Hypercoagulation Plasma Haemostasis Objectives: To study changes in the parameters of thromboelastometry and the plasma link of the hemostasis system in women with uncomplicated pregnancy and with manifestations of thrombophilia in the perinatal period. Methods: The analysis of indices of thromboelastometry and coagulogram in 408 women was conducted. The study was conducted from 8.09.2016 for 13.09.2016. The subjects were conventionally divided into groups: A - women without pathology of hemostasis (n = 152), B - women with clinical manifestations of thrombophilia (n = 256). The examination was carried out in the third trimester of pregnancy, on days 1 and 5 after delivery. Results: In patients with thrombophilia, significant changes in coagulation potentials, characterized by hypercoagulation, thrombinemia and a decrease in the reserve of natural anticoagulants, and a decrease in fibrinolysis activity were noted. Changes were observed in the prenatal period, increased in the first day after childbirth. Conclusion: The studied parameters of hemostasis can be used in assessing the risk of thrombotic complications and the rationale for antithrombotic therapy. The hemostatic system is one of the fundamental systems of the human body, which ensures the functioning of all organs. During pregnancy are hemostatic changes which are intended at maintaining normal functioning of the fetoplacental complex and stop bleeding from the vessels of the placental bed after the separation of the placenta. Moreover, in the course of gestation, the conditions for the development of a hypercoagulable state and complications of pregnancy 2018-06-06T14:46:48Z 2018-06-06T14:46:48Z 2018 Статья Muratova, AY; Denisova, EV; Melchenko, EA; Gligova, TN; Andrusenko, SF; Suprunchuk, VE. Changes of hemostasis indicators in women in accuracy practice // ENTOMOLOGY AND APPLIED SCIENCE LETTERS. - 2018. - Volume 5. - Issue 1. - Pages 27 - 30 http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=1&SID=D4CqLgJyMUbdkXB1tTT&page=1&doc=27 https://dspace.ncfu.ru:443/handle/20.500.12258/492 en ENTOMOLOGY AND APPLIED SCIENCE LETTERS application/pdf ENTOMOLOGY & APPLIED SCIENCE RESEARCH LETTERS-EASLETTERS
institution	СКФУ
collection	Репозиторий
language	English
topic	Pregnant Women Thrombophilia Thromboelastometry Hypercoagulation Plasma Haemostasis
spellingShingle	Pregnant Women Thrombophilia Thromboelastometry Hypercoagulation Plasma Haemostasis Muratova, A. Y. Муратова, А. Ю. Denisova, E. V. Денисова, Е. В. Melchenko, E. A. Мельченко, Е. А. Glizhova, T. N. Глижова, Т. Н. Andrusenko, S. F. Андрусенко, С. Ф. Suprunchuk, V. E. Супрунчук, В. Е. Changes of hemostasis indicators in women in accuracy practice
description	Objectives: To study changes in the parameters of thromboelastometry and the plasma link of the hemostasis system in women with uncomplicated pregnancy and with manifestations of thrombophilia in the perinatal period. Methods: The analysis of indices of thromboelastometry and coagulogram in 408 women was conducted. The study was conducted from 8.09.2016 for 13.09.2016. The subjects were conventionally divided into groups: A - women without pathology of hemostasis (n = 152), B - women with clinical manifestations of thrombophilia (n = 256). The examination was carried out in the third trimester of pregnancy, on days 1 and 5 after delivery. Results: In patients with thrombophilia, significant changes in coagulation potentials, characterized by hypercoagulation, thrombinemia and a decrease in the reserve of natural anticoagulants, and a decrease in fibrinolysis activity were noted. Changes were observed in the prenatal period, increased in the first day after childbirth. Conclusion: The studied parameters of hemostasis can be used in assessing the risk of thrombotic complications and the rationale for antithrombotic therapy. The hemostatic system is one of the fundamental systems of the human body, which ensures the functioning of all organs. During pregnancy are hemostatic changes which are intended at maintaining normal functioning of the fetoplacental complex and stop bleeding from the vessels of the placental bed after the separation of the placenta. Moreover, in the course of gestation, the conditions for the development of a hypercoagulable state and complications of pregnancy
format	Статья
author	Muratova, A. Y. Муратова, А. Ю. Denisova, E. V. Денисова, Е. В. Melchenko, E. A. Мельченко, Е. А. Glizhova, T. N. Глижова, Т. Н. Andrusenko, S. F. Андрусенко, С. Ф. Suprunchuk, V. E. Супрунчук, В. Е.
author_facet	Muratova, A. Y. Муратова, А. Ю. Denisova, E. V. Денисова, Е. В. Melchenko, E. A. Мельченко, Е. А. Glizhova, T. N. Глижова, Т. Н. Andrusenko, S. F. Андрусенко, С. Ф. Suprunchuk, V. E. Супрунчук, В. Е.
author_sort	Muratova, A. Y.
title	Changes of hemostasis indicators in women in accuracy practice
title_short	Changes of hemostasis indicators in women in accuracy practice
title_full	Changes of hemostasis indicators in women in accuracy practice
title_fullStr	Changes of hemostasis indicators in women in accuracy practice
title_full_unstemmed	Changes of hemostasis indicators in women in accuracy practice
title_sort	changes of hemostasis indicators in women in accuracy practice
publisher	ENTOMOLOGY & APPLIED SCIENCE RESEARCH LETTERS-EASLETTERS
publishDate	2018
url	http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=1&SID=D4CqLgJyMUbdkXB1tTT&page=1&doc=27 https://dspace.ncfu.ru:443/handle/20.500.12258/492
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Changes of hemostasis indicators in women in accuracy practice

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