Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides

The aminomethylation of 4,4-dialkyl-2,6-dioxopiperidine-3,5-dicarbonitriles (Guareschi imides) was studied for the first time. When the Guareschi imides were treated with primary aliphatic amines and an excess of formaldehyde, 2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitriles were obtained...

Полное описание

Сохранить в:

Библиографические подробности
Главные авторы:	Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Формат:	Статья
Язык:	English
Опубликовано:	Elsevier Ltd 2018
Темы:	2,6-Dioxopiperidine-3,5-dicarbonitriles 3,7-Diazabicyclo[3.3.1]nonanes Guareschi imides Mannich reaction
Online-ссылка:	https://dspace.ncfu.ru:443/handle/20.500.12258/497
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!

id	ir-20.500.12258-497
record_format	dspace
spelling	ir-20.500.12258-4972025-02-12T12:49:17Z Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. 2,6-Dioxopiperidine-3,5-dicarbonitriles 3,7-Diazabicyclo[3.3.1]nonanes Guareschi imides Mannich reaction The aminomethylation of 4,4-dialkyl-2,6-dioxopiperidine-3,5-dicarbonitriles (Guareschi imides) was studied for the first time. When the Guareschi imides were treated with primary aliphatic amines and an excess of formaldehyde, 2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitriles were obtained in varying yields (15–67%). The structure of 9,9-dimethyl-7-(2-methylpropyl)-2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitrile was studied by X-ray diffraction analysis 2018-06-07T09:57:18Z 2018-06-07T09:57:18Z 2017 Статья Khrustaleva, A.N., Frolov, K.A., Dotsenko, V.V., Aksenov, N.A., Aksenova, I.V., Krivokolysko, S.G. Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides // Tetrahedron Letters. - 2018. - Volume 58. - Issue 50. - pp. 4663-4666. https://dspace.ncfu.ru:443/handle/20.500.12258/497 en Tetrahedron Letters application/pdf application/pdf Elsevier Ltd
institution	СКФУ
collection	Репозиторий
language	English
topic	2,6-Dioxopiperidine-3,5-dicarbonitriles 3,7-Diazabicyclo[3.3.1]nonanes Guareschi imides Mannich reaction
spellingShingle	2,6-Dioxopiperidine-3,5-dicarbonitriles 3,7-Diazabicyclo[3.3.1]nonanes Guareschi imides Mannich reaction Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В. Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
description	The aminomethylation of 4,4-dialkyl-2,6-dioxopiperidine-3,5-dicarbonitriles (Guareschi imides) was studied for the first time. When the Guareschi imides were treated with primary aliphatic amines and an excess of formaldehyde, 2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitriles were obtained in varying yields (15–67%). The structure of 9,9-dimethyl-7-(2-methylpropyl)-2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitrile was studied by X-ray diffraction analysis
format	Статья
author	Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В.
author_facet	Dotsenko, V. V. Доценко, В. В. Aksenov, N. A. Аксенов, Н. А. Aksenova, I. V. Аксенова, И. В.
author_sort	Dotsenko, V. V.
title	Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
title_short	Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
title_full	Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
title_fullStr	Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
title_full_unstemmed	Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides
title_sort	synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the guareschi imides
publisher	Elsevier Ltd
publishDate	2018
url	https://dspace.ncfu.ru:443/handle/20.500.12258/497
work_keys_str_mv	AT dotsenkovv synthesisofnewfunctionalized37diazabicyclo331nonanesbyaminomethylationoftheguareschiimides AT docenkovv synthesisofnewfunctionalized37diazabicyclo331nonanesbyaminomethylationoftheguareschiimides AT aksenovna synthesisofnewfunctionalized37diazabicyclo331nonanesbyaminomethylationoftheguareschiimides AT aksenovna synthesisofnewfunctionalized37diazabicyclo331nonanesbyaminomethylationoftheguareschiimides AT aksenovaiv synthesisofnewfunctionalized37diazabicyclo331nonanesbyaminomethylationoftheguareschiimides AT aksenovaiv synthesisofnewfunctionalized37diazabicyclo331nonanesbyaminomethylationoftheguareschiimides
_version_	1842245570981265408

Synthesis of new functionalized 3,7-diazabicyclo[3.3.1]nonanes by aminomethylation of the Guareschi imides

Схожие документы