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New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles

The review summarizes the results obtained by our research group over the past 15 years in chemistry of N-, S,N-, and Se,N-heterocycles resulted from aminomethlation of a wide range of acyclic and heterocyclic substrates derived from active methylene amides, thioamides, and selenoamides. A series of...

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Главные авторы: Dotsenko, V. V., Доценко, В. В.
格式: Статья
语言:English
出版: SPRINGER 2019
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https://dspace.ncfu.ru/handle/20.500.12258/5561
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spelling ir-20.500.12258-55612020-02-17T12:42:33Z New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles Dotsenko, V. V. Доценко, В. В. Heterocyclization Cyanoselenoacetamide Aminomethylation Mannich reaction Active methylene chalcogen amides Cyanothioacetamide Selenoamides The review summarizes the results obtained by our research group over the past 15 years in chemistry of N-, S,N-, and Se,N-heterocycles resulted from aminomethlation of a wide range of acyclic and heterocyclic substrates derived from active methylene amides, thioamides, and selenoamides. A series of 1,3,5-thia(selena)diazines, 3,7-diazabicyclo[3.3.1] nonanes, 3,5,7,11-tetraazatricyclo[7.3.1.0(2,7)]tridec-2-enes, 1,3,5,7-tetrazocines, and pyrido[1,2-a][1,3,5]triazines were synthesized. The general regularities of the Mannich reaction in the series of N-, S,N-, and Se,N-containing pyridine substrates were discussed. Biological activities of some synthesized compounds were studied to reveal compounds with antiviral, analeptic, anti-inflammatory, and antipyretic activities 2019-06-07T14:02:02Z 2019-06-07T14:02:02Z 2019 Статья Dotsenko, VV; Frolov, KA; Chigorina, EA; Khrustaleva, AN; Bibik, EY; Krivokolysko, SG. New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles // RUSSIAN CHEMICAL BULLETIN. - 2019. - Том: 68. - Выпуск: 4. - Стр.: 691-707 http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=38&SID=E1BmcFx8KXF5GsBSl3h&page=1&doc=1 http://hdl.handle.net/20.500.12258/5561 en Russian Chemical Bulletin application/pdf application/pdf SPRINGER
institution СКФУ
collection Репозиторий
language English
topic Heterocyclization
Cyanoselenoacetamide
Aminomethylation
Mannich reaction
Active methylene chalcogen amides
Cyanothioacetamide
Selenoamides
spellingShingle Heterocyclization
Cyanoselenoacetamide
Aminomethylation
Mannich reaction
Active methylene chalcogen amides
Cyanothioacetamide
Selenoamides
Dotsenko, V. V.
Доценко, В. В.
New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
description The review summarizes the results obtained by our research group over the past 15 years in chemistry of N-, S,N-, and Se,N-heterocycles resulted from aminomethlation of a wide range of acyclic and heterocyclic substrates derived from active methylene amides, thioamides, and selenoamides. A series of 1,3,5-thia(selena)diazines, 3,7-diazabicyclo[3.3.1] nonanes, 3,5,7,11-tetraazatricyclo[7.3.1.0(2,7)]tridec-2-enes, 1,3,5,7-tetrazocines, and pyrido[1,2-a][1,3,5]triazines were synthesized. The general regularities of the Mannich reaction in the series of N-, S,N-, and Se,N-containing pyridine substrates were discussed. Biological activities of some synthesized compounds were studied to reveal compounds with antiviral, analeptic, anti-inflammatory, and antipyretic activities
format Статья
author Dotsenko, V. V.
Доценко, В. В.
author_facet Dotsenko, V. V.
Доценко, В. В.
author_sort Dotsenko, V. V.
title New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
title_short New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
title_full New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
title_fullStr New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
title_full_unstemmed New possibilities of the Mannich reaction in the synthesis of N-, S,N-, and Se,N-heterocycles
title_sort new possibilities of the mannich reaction in the synthesis of n-, s,n-, and se,n-heterocycles
publisher SPRINGER
publishDate 2019
url http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=38&SID=E1BmcFx8KXF5GsBSl3h&page=1&doc=1
https://dspace.ncfu.ru/handle/20.500.12258/5561
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