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Michael addition to 3-(2-nitrovinyl)indoles – route toward aliphatic nitro compounds with heterocyclic substituents

Michael addition to 3-(2-nitrovinyl)indoles – route toward aliphatic nitro compounds with heterocyclic substituents

Synthetic approach toward indole derivatives bearing 2-nitroethyl group and polar azole moiety has been developed. This method involves conjugate addition of 1,3-dicarbonyl compounds to 3-(2-nitrovinyl)-1H-indoles followed by cyclocondensation with hydrazine or hydroxylamine to furnish pyrazole or i...

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Podrobná bibliografie
Hlavní autoři: Aksenov, N. A., Аксенов, Н. А., Skomorokhov, A. A., Скоморохов, А. А., Aksenov, A. V., Аксенов, А. В., Rubin, M. A., Рубин, М. А.
Médium: Статья
Jazyk:English
Vydáno: Springer New York LLC 2019
Témata:
Indole
Isoxazole
Michael addition
Microwave-assisted synthesis
Nitroalkenes
Pyrazole
On-line přístup:https://www.scopus.com/record/display.uri?eid=2-s2.0-85070100471&origin=resultslist&sort=plf-f&src=s&st1=Michael+addition+to+3-2-nitrovinyl+indoles+--+route+toward+aliphatic+nitro+compounds+with+heterocyclic+substituents&st2=&sid=1c5a6fe41babdcf93eed0c3d463275ee&sot=b&sdt=b&sl=130&s=TITLE-ABS-KEY%28Michael+addition+to+3-2-nitrovinyl+indoles+--+route+toward+aliphatic+nitro+compounds+with+heterocyclic+substituents%29&relpos=0&citeCnt=0&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/7502
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https://www.scopus.com/record/display.uri?eid=2-s2.0-85070100471&origin=resultslist&sort=plf-f&src=s&st1=Michael+addition+to+3-2-nitrovinyl+indoles+--+route+toward+aliphatic+nitro+compounds+with+heterocyclic+substituents&st2=&sid=1c5a6fe41babdcf93eed0c3d463275ee&sot=b&sdt=b&sl=130&s=TITLE-ABS-KEY%28Michael+addition+to+3-2-nitrovinyl+indoles+--+route+toward+aliphatic+nitro+compounds+with+heterocyclic+substituents%29&relpos=0&citeCnt=0&searchTerm=
https://dspace.ncfu.ru/handle/20.500.12258/7502

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