Preparation of stereodefined 2-(3-Oxoindolin-2-yl)-2-arylacetonitriles via one-pot reaction of indoles with nitroalkenes

Preparation of stereodefined 2-(3-Oxoindolin-2-yl)-2-arylacetonitriles via one-pot reaction of indoles with nitroalkenes

Recently discovered reactivity of nitrostyrenes in phosphorous acid to facilitate the diastereoselective [4 + 1]-cycloaddition of indoles in combination with unusual oxazoline ring cleavage and subsequent 1,2-alkyl shift afforded stereochemically defined 2-(3-oxoindolin-2-yl)-2-arylacetonitriles as...

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Главные авторы:	Aksenov, A. V., Аксенов, А. В., Aksenov, D. A., Аксенов, Д. А., Aksenov, N. A., Аксенов, Н. А., Aleksandrova, E. V., Александрова, Е. В., Rubin, M. A., Рубин, М. А.
Формат:	Статья
Язык:	English
Опубликовано:	American Chemical Society 2019
Темы:	Chemistry Diastereoselective Nitroalkenes One-pot reaction Oxazoline ring Phosphorous acid Organic compounds
Online-ссылка:	https://dspace.ncfu.ru/handle/20.500.12258/8015
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