Synthesis and properties of new fluorine-containing thieno[2,3-b]pyridine derivatives

Synthesis and properties of new fluorine-containing thieno[2,3-b]pyridine derivatives

Cyanothioacetamide reacted with 1,1,5,5-tetrafluoroacetylacetone to give 4,6-bis(difluoromethyl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile, and alkylation of the latter with α-chloroacetamides afforded 3-amino-4,6-bis(difluoromethyl)thieno[2,3-b]pyridine-2-carboxamides. The structure of the key co...

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Главные авторы:	Dotsenko, V. V., Доценко, В. В., Aksenov, N. A., Аксенов, Н. А., Aksenova, I. V., Аксенова, И. В.
Формат:	Статья
Язык:	English
Опубликовано:	Pleiades Publishing 2019
Темы:	Cyanothioacetamide Guareschi-Thorpe reaction In silico biological activity Organic fluorides Thieno[2,3-b]pyridines Thorpe-Ziegler cyclization
Online-ссылка:	https://dspace.ncfu.ru/handle/20.500.12258/8307
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!

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