One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine

Indolo[3,2-c]quinolones have been efficiently synthesized via an acid-mediated, one-pot, three-component condensation of arylhydrazines, o-aminoacetophenones, and triazines or nitriles. The synthetic application of this method is showcased by the concise synthesis of isocryptolepine alkaloid and a s...

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Glavni autori:	Aksenov, A. V., Аксенов, А. В., Aksenov, D. A., Аксенов, Д. А., Orazova, N. A., Оразова, Н. А., Aksenov, N. A., Аксенов, Н. А., Griaznov, G. D., Грязнов, Г. Д., Rubin, M. A., Рубин, М. А.
Format:	Статья
Jezik:	English
Izdano:	American Chemical Society 2018
Teme:	Anti-proliferative activities Chemistry Arylhydrazines Synthetic analogues Synthetic application Three component Total synthesis
Online pristup:	https://www.scopus.com/record/display.uri?eid=2-s2.0-85015621562&origin=resultslist&sort=plf-f&src=s&nlo=&nlr=&nls=&sid=ed251e00f055bf6a464fa9575f335a90&sot=aff&sdt=sisr&sl=174&s=AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29+OR+AF-ID%28%22Stavropol+State+University%22+60070961%29+OR+AF-ID%28%22stavropolskij+Gosudarstvennyj+Tehniceskij+Universitet%22+60026323%29&ref=%28One-Pot%2c+Three-Component+Assembly+of+Indoloquinolines%3a+Total+Synthesis+of+Isocryptolepine%29&relpos=2&citeCnt=4&searchTerm= https://dspace.ncfu.ru/handle/20.500.12258/3070
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spelling	oai:10.200.131.19:20.500.12258-30702018-09-25T14:10:37Z One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine Aksenov, A. V. Аксенов, А. В. Aksenov, D. A. Аксенов, Д. А. Orazova, N. A. Оразова, Н. А. Aksenov, N. A. Аксенов, Н. А. Griaznov, G. D. Грязнов, Г. Д. Rubin, M. A. Рубин, М. А. Anti-proliferative activities Chemistry Arylhydrazines Synthetic analogues Synthetic application Three component Total synthesis Indolo[3,2-c]quinolones have been efficiently synthesized via an acid-mediated, one-pot, three-component condensation of arylhydrazines, o-aminoacetophenones, and triazines or nitriles. The synthetic application of this method is showcased by the concise synthesis of isocryptolepine alkaloid and a series of its synthetic analogues with demonstrated cancer cell antiproliferative activities 2018-09-25T14:10:01Z 2018-09-25T14:10:01Z 2017 Статья Aksenov, A.V., Aksenov, D.A., Orazova, N.A., Aksenov, N.A., Griaznov, G.D., De Carvalho, A., Kiss, R., Mathieu, V., Kornienko, A., Rubin, M. One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine // Journal of Organic Chemistry. - 2017. - Volume 82. - Issue 6. - Pages 3011-3018 https://www.scopus.com/record/display.uri?eid=2-s2.0-85015621562&origin=resultslist&sort=plf-f&src=s&nlo=&nlr=&nls=&sid=ed251e00f055bf6a464fa9575f335a90&sot=aff&sdt=sisr&sl=174&s=AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29+OR+AF-ID%28%22Stavropol+State+University%22+60070961%29+OR+AF-ID%28%22stavropolskij+Gosudarstvennyj+Tehniceskij+Universitet%22+60026323%29&ref=%28One-Pot%2c+Three-Component+Assembly+of+Indoloquinolines%3a+Total+Synthesis+of+Isocryptolepine%29&relpos=2&citeCnt=4&searchTerm= http://hdl.handle.net/20.500.12258/3070 en Journal of Organic Chemistry application/pdf application/pdf American Chemical Society
institution	СКФУ
collection	Репозиторий
language	English
topic	Anti-proliferative activities Chemistry Arylhydrazines Synthetic analogues Synthetic application Three component Total synthesis
spellingShingle	Anti-proliferative activities Chemistry Arylhydrazines Synthetic analogues Synthetic application Three component Total synthesis Aksenov, A. V. Аксенов, А. В. Aksenov, D. A. Аксенов, Д. А. Orazova, N. A. Оразова, Н. А. Aksenov, N. A. Аксенов, Н. А. Griaznov, G. D. Грязнов, Г. Д. Rubin, M. A. Рубин, М. А. One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
description	Indolo[3,2-c]quinolones have been efficiently synthesized via an acid-mediated, one-pot, three-component condensation of arylhydrazines, o-aminoacetophenones, and triazines or nitriles. The synthetic application of this method is showcased by the concise synthesis of isocryptolepine alkaloid and a series of its synthetic analogues with demonstrated cancer cell antiproliferative activities
format	Статья
author	Aksenov, A. V. Аксенов, А. В. Aksenov, D. A. Аксенов, Д. А. Orazova, N. A. Оразова, Н. А. Aksenov, N. A. Аксенов, Н. А. Griaznov, G. D. Грязнов, Г. Д. Rubin, M. A. Рубин, М. А.
author_facet	Aksenov, A. V. Аксенов, А. В. Aksenov, D. A. Аксенов, Д. А. Orazova, N. A. Оразова, Н. А. Aksenov, N. A. Аксенов, Н. А. Griaznov, G. D. Грязнов, Г. Д. Rubin, M. A. Рубин, М. А.
author_sort	Aksenov, A. V.
title	One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
title_short	One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
title_full	One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
title_fullStr	One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
title_full_unstemmed	One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine
title_sort	one-pot, three-component assembly of indoloquinolines: total synthesis of isocryptolepine
publisher	American Chemical Society
publishDate	2018
url	https://www.scopus.com/record/display.uri?eid=2-s2.0-85015621562&origin=resultslist&sort=plf-f&src=s&nlo=&nlr=&nls=&sid=ed251e00f055bf6a464fa9575f335a90&sot=aff&sdt=sisr&sl=174&s=AF-ID%28%22North+Caucasus+Federal+University%22+60070541%29+OR+AF-ID%28%22Stavropol+State+University%22+60070961%29+OR+AF-ID%28%22stavropolskij+Gosudarstvennyj+Tehniceskij+Universitet%22+60026323%29&ref=%28One-Pot%2c+Three-Component+Assembly+of+Indoloquinolines%3a+Total+Synthesis+of+Isocryptolepine%29&relpos=2&citeCnt=4&searchTerm= https://dspace.ncfu.ru/handle/20.500.12258/3070
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One-Pot, Three-Component Assembly of Indoloquinolines: Total Synthesis of Isocryptolepine

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