2-(3-Indolyl)acetamides and their oxazoline analogues: Anticancer SAR study
We previously studied 2-aryl-2-(3-indolyl)acetohydroxamates as potential agents against melanoma. These compounds were ineffective in a mouse melanoma xenograft model, most likely due to unfavorable metabolic properties, specifically due to glucuronidation of the N-hydroxyl of the hydoxamic moiety....
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| Главные авторы: | , , , , , , , , , , , |
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| Formato: | Статья |
| Idioma: | English |
| Publicado em: |
2024
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| Assuntos: | |
| Acesso em linha: | https://dspace.ncfu.ru/handle/123456789/27069 |
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