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2-(3-Indolyl)acetamides and their oxazoline analogues: Anticancer SAR study

2-(3-Indolyl)acetamides and their oxazoline analogues: Anticancer SAR study

We previously studied 2-aryl-2-(3-indolyl)acetohydroxamates as potential agents against melanoma. These compounds were ineffective in a mouse melanoma xenograft model, most likely due to unfavorable metabolic properties, specifically due to glucuronidation of the N-hydroxyl of the hydoxamic moiety....

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Detaylı Bibliyografya
Asıl Yazarlar: Aksenov, D. A., Аксенов, Д. А., Aksenov, A. V., Аксенов, А. В., Prityko, L. A., Притыко, Л. А., Aksenov, N. A., Аксенов, Н. А., Kuzminov, I. K., Кузьминов, И. К., Aleksandrova, E. V., Александрова, Е. В.
Materyal Türü: Статья
Dil:English
Baskı/Yayın Bilgisi: 2024
Konular:
Anticancer activity
Neuroblastoma
Hydroxamate
Indoles
Oxazoline
Online Erişim:https://dspace.ncfu.ru/handle/123456789/27069
Etiketler: Etiketle
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https://dspace.ncfu.ru/handle/123456789/27069

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