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γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles

Here, we describe the one-pot assembly of imidazo[1,2-a]pyridine and quinoxaline heterocyclic cores by the electrophilic tandem cyclization between 3,5-diaryl substituted 5-hydroxy-3-pyrrolin-2-ones and the corresponding nitrogen bis-nucleophiles. This microwave-assisted annulation occurs in superhe...

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Главные авторы: Aksenov, N. A., Аксенов, Н. А., Kurenkov, I. A., Куренков, И. А., Arutiunov, N. A., Арутюнов, Н. А., Malyuga, V. V., Малюга, В. В., Aksenov, D. A., Аксенов, Д. А., Leontiev, A. V., Леонтьев, А. В., Aksenov, A. V., Аксенов, А. В.
Формат: Статья
Язык:English
Опубликовано: Royal Society of Chemistry 2024
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Online-ссылка:https://dspace.ncfu.ru/handle/123456789/28981
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spelling ir-123456789-289812024-09-16T13:57:05Z γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles Aksenov, N. A. Аксенов, Н. А. Kurenkov, I. A. Куренков, И. А. Arutiunov, N. A. Арутюнов, Н. А. Malyuga, V. V. Малюга, В. В. Aksenov, D. A. Аксенов, Д. А. Leontiev, A. V. Леонтьев, А. В. Aksenov, A. V. Аксенов, А. В. 5-hydroxy-3-pyrrolin-2-ones Positive ions Acid-free Butyrolactams Microwave-assisted Nitrogen heterocycles Electrophiles Lewis Acid Quinoxalines One pot Tandem cyclization Microwave radiation Here, we describe the one-pot assembly of imidazo[1,2-a]pyridine and quinoxaline heterocyclic cores by the electrophilic tandem cyclization between 3,5-diaryl substituted 5-hydroxy-3-pyrrolin-2-ones and the corresponding nitrogen bis-nucleophiles. This microwave-assisted annulation occurs in superheated water and does not require the addition of any acid. 2024-09-16T13:52:22Z 2024-09-16T13:52:22Z 2024 Статья Aksenov, N.A., Kurenkov, I.A., Arutiunov, N.A., Malyuga, V.V., Aksenov, D.A., Leontiev, A.V., Aksenov, A.V. γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles // New Journal of Chemistry. - 2024. - 48 (31). - pp. 13752-13763. - DOI: 10.1039/d4nj01595a https://dspace.ncfu.ru/handle/123456789/28981 en New Journal of Chemistry application/pdf application/pdf Royal Society of Chemistry
institution СКФУ
collection Репозиторий
language English
topic 5-hydroxy-3-pyrrolin-2-ones
Positive ions
Acid-free
Butyrolactams
Microwave-assisted
Nitrogen heterocycles
Electrophiles
Lewis Acid
Quinoxalines
One pot
Tandem cyclization
Microwave radiation
spellingShingle 5-hydroxy-3-pyrrolin-2-ones
Positive ions
Acid-free
Butyrolactams
Microwave-assisted
Nitrogen heterocycles
Electrophiles
Lewis Acid
Quinoxalines
One pot
Tandem cyclization
Microwave radiation
Aksenov, N. A.
Аксенов, Н. А.
Kurenkov, I. A.
Куренков, И. А.
Arutiunov, N. A.
Арутюнов, Н. А.
Malyuga, V. V.
Малюга, В. В.
Aksenov, D. A.
Аксенов, Д. А.
Leontiev, A. V.
Леонтьев, А. В.
Aksenov, A. V.
Аксенов, А. В.
γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles
description Here, we describe the one-pot assembly of imidazo[1,2-a]pyridine and quinoxaline heterocyclic cores by the electrophilic tandem cyclization between 3,5-diaryl substituted 5-hydroxy-3-pyrrolin-2-ones and the corresponding nitrogen bis-nucleophiles. This microwave-assisted annulation occurs in superheated water and does not require the addition of any acid.
format Статья
author Aksenov, N. A.
Аксенов, Н. А.
Kurenkov, I. A.
Куренков, И. А.
Arutiunov, N. A.
Арутюнов, Н. А.
Malyuga, V. V.
Малюга, В. В.
Aksenov, D. A.
Аксенов, Д. А.
Leontiev, A. V.
Леонтьев, А. В.
Aksenov, A. V.
Аксенов, А. В.
author_facet Aksenov, N. A.
Аксенов, Н. А.
Kurenkov, I. A.
Куренков, И. А.
Arutiunov, N. A.
Арутюнов, Н. А.
Malyuga, V. V.
Малюга, В. В.
Aksenov, D. A.
Аксенов, Д. А.
Leontiev, A. V.
Леонтьев, А. В.
Aksenov, A. V.
Аксенов, А. В.
author_sort Aksenov, N. A.
title γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles
title_short γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles
title_full γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles
title_fullStr γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles
title_full_unstemmed γ-Hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a Brønsted/Lewis acid-free synthesis of condensed nitrogen heterocycles
title_sort γ-hydroxy-γ-butyrolactams as 1,2-bis-electrophiles in a brønsted/lewis acid-free synthesis of condensed nitrogen heterocycles
publisher Royal Society of Chemistry
publishDate 2024
url https://dspace.ncfu.ru/handle/123456789/28981
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